284465-79-8Relevant academic research and scientific papers
Certain 2-furano-4(3H)-quinazolinone analogs: Synthesis, characterization and pharmacological evaluation
Bhardwaj, Varun,Sharma, Poonam,Noolvi, Malleshappa N.,Patel, Harun M.,Bansal, Sumit,Lohan, Sandeep,Badola, Gaurav
, p. 360 - 368 (2013/07/26)
A series of new of 2-furano-4(3H)-quinazolinone derivatives 5 (a-t) were synthesized. The compounds were characterized by their IR, 1H NMR, 13C NMR, and Mass spectral data. The antimicrobial activity of newly anthranilic acid-based compounds against various bacteria; S. aureus, Salmonella enterica, Vibrio cholerae, Bacillus subtilis, Proteus mirabili, Escherichia coli V517, Mycobacterium smegmatics, Pseudomonas aeruginosa and fungi; C. albicans, were evaluated with ampicillin and amphotericin B as standards. All compounds were also evaluated for antibacterial activity against R. solanacearum along with Kocide 3000 as a commercialized reference. Compounds 5d, 5g, 5j, 5l, 5q, 5r, 5s, and 5t exhibited good potential as antimicrobial.
