28447-26-9

Usage

Uses

Used in Flame Retardant Industry:
DIMETHYL PHTHALIMIDOMETHYLPHOSPHONATE is used as a flame retardant for its ability to prevent or slow down the spread of fire in materials, enhancing their fire resistance.
Used in Plastics and Polyurethane Foam Production:
DIMETHYL PHTHALIMIDOMETHYLPHOSPHONATE is used as a key component in the production of polyurethane foam and other plastics, contributing to their flame retardant properties and improving their safety in various applications.
Used in Industrial Applications:
DIMETHYL PHTHALIMIDOMETHYLPHOSPHONATE is used as an additive in a variety of industrial applications, providing enhanced thermal stability and flame retardancy to the products.
It is important to handle DIMETHYL PHTHALIMIDOMETHYLPHOSPHONATE with care and follow proper safety precautions, as it can be harmful if ingested or inhaled, and can cause skin and eye irritation.

InChI:InChI=1/C11H12NO5P/c1-16-18(15,17-2)7-12-10(13)8-5-3-4-6-9(8)11(12)14/h3-6H,7H2,1-2H3

Upstream product

• 5332-26-3 N-(bromomethyl)phtalimide 
• 1914-20-1 N-methoxyphthalimide 
• 121-45-9 phosphorous acid trimethyl ester 

Downstream Products

• 1445-69-8 2,3-dihydrophthalazine-1,4-dione 
• 50918-71-3 dimethyl (aminomethyl)phosphonate 

Relevant academic research and scientific papers

Michaelis-Arbuzov-type reaction of 1-imidoalkyltriarylphosphonium salts with selected phosphorus nucleophiles

In this study, Michaelis-Arbuzov-type reaction of 1-imidoalkyltriarylphosphonium salts with phosphites, phosphonites, and phosphinites was used in the synthesis of a wide range of phosphorus analogs of α-amino acids such as 1-imidoalkylphosphonates, 1-imidoalkylphosphinates, and 1-imidoalkylphosphine oxides. Large differences were observed in the reactivity of substrates depending on their structure, especially on the type of phosphonium moiety and N-protecting group. The conditions under which the expected products can be obtained in good to excellent yields have been developed. Mechanistic aspects of the transformation have been provided.

Efficient synthesis routes for various phthalimido phosphor esters as antimicrobial agents in terms of structure-activity relationship

A series of phthalimido phosphor derivatives α-amino-phosphonates, amidophosphonates, phosphonic acid diamides, and oxadiazaphospholes-were prepared by applying different types of phosphorus(III) reagents to 2-methoxy-1H-isoindole-1,3(2H)-dione and 2-anilino-1H-isoindole-1,3(2H)-dione. On the basis of bioassay results, some of the new phosphoryl imides could be considered as lead molecules to be modified in order to improve their antibiotic activity. Springer-Verlag 2010.

Inhibitors of β-lactamase

The intention relates to bacterial antibiotic resistance and, in particular, to compositions and methods for overcoming bacterial antibiotic resistance. The invention provides novel β-lactamase inhibitors, which are structurally unrelated to the natural p

Novel inhibitors of beta-lactamase

The intention relates to bacterial antibiotic resistance and, in particular, to compositions and methods for overcoming bacterial antibiotic resistance. The invention provides novel β-lactamase inhibitors, which are structurally unrelated to the natural p

Novel Inhibitors of beta-lactamase

The invention relates to bacterial antibiotic resistance and, in particular, to compositions and methods for overcoming bacterial antibiotic resistance. The invention provides novel β-lactamase inhibitors, which are structurally unrelated to the natural p

Sulfonamidomethyl phosphonate inhibitors of beta-lactamase

The intention relates to bacterial antibiotic resistance and, in particular, to compositions and methods for overcoming bacterial antibiotic resistance. The invention provides novel β-lactamase inhibitors, which are structurally unrelated to the natural p

7β-Acylamino-3-(phosphonoalkyl and esterified phosphonoalkyl substituted tetrazolylthiomethyl)cephalosporins

The compounds of this invention are cephalosporins having various acylamino substituents at the 7-position and a phosphonoalkyl or esterified phosphonoalkyl substituted tetrazolylthiomethyl group at the 3-position of the cephem nucleus and intermediates for the preparation thereof. The 7-acylated compounds have antibacterial activity.