2845-28-5Relevant articles and documents
Rhodium-Catalyzed Asymmetric Conjugate Alkynylation of β,γ-Unsaturated α-Ketoesters
Zhi, Yanle,Huang, Jianhang,Liu, Na,Lu, Tao,Dou, Xiaowei
, p. 2378 - 2381 (2017)
The first example of catalytic asymmetric conjugate alkynylation of β,γ-unsaturated α-ketoesters is reported. By using Rh(I)/(R)-DM-binap complex as the catalyst and diphenyl[(triisopropylsilyl)ethynyl]methanol as the alkynylating reagent, the alkynylation reaction proceeded smoothly to afford α-ketoesters bearing a propargylic chiral center at γ position in good yields with high enantioselectivities.
Alkyl Ethers as Traceless Hydride Donors in Br?nsted Acid Catalyzed Intramolecular Hydrogen Atom Transfer
Gandamana, Dhika Aditya,Wang, Bin,Tejo, Ciputra,Bolte, Benoit,Gagosz, Fabien,Chiba, Shunsuke
, p. 6181 - 6185 (2018/05/03)
A new protocol for the deoxygenation of alcohols and the hydrogenation of alkenes under Br?nsted acid catalysis has been developed. The method is based on the use of either a benzyl or isopropyl ether as a traceless hydrogen-atom donor, and involves an intramolecular hydride transfer as a key step, which is achieved in a regio- and stereoselective manner.
Enantioselective halogenative semi-pinacol rearrangement: A stereodivergent reaction on a racemic mixture
Romanov-Michailidis, Fedor,Pupier, Marion,Gune, Laure,Alexakis, Alexandre
, p. 13461 - 13464 (2015/02/19)
An efficient, quantitative deracemization strategy for optically inactive allylic cycloalkanols has been achieved using the biphasic halogenative semi-pinacol reaction protocol. The resultant β-halo spiroketones, containing three contiguous stereogenic ce
