137151-89-4

Upstream product

• 2845-28-5 (-)-(R)-3-phenylpentan-1-ol 
• 137151-88-3 (3R)-3-cyclohexyl-1-(trimethylsilyl)-1-pentanol 
• 2043-61-0 cyclohexanecarbaldehyde 
• 137151-58-7 (E)-3-cyclohexyl-2-propenyl 1-(trimethylsilyl)vinyl ether 
• 6048-09-5 3-cyclohexylacrylic acid ethyl ester 
• 129520-89-4 (S)-3-cyclohexyl-1-(trimethylsilyl)-4-penten-1-one 
• 42134-55-4 (E)-3-cyclohexyl-2-propen-1-ol 

Relevant academic research and scientific papers

Enantioselective activation of ethers by chiral organoaluminum reagents: Application to asymmetric Claisen rearrangement

The asymmetric Claisen rearrangement of allyl vinyl ethers has been effected with a chiral organoaluminum reagent, (R)-1 or (S)-1 as an example of the enantioselectie activation of ether substrates. This method provides a facile asymmetric synthesis of various acylsilanes and acylgermanes with high optical purity. Among various trialkylsilyl substituents of chiral organoaluminum reagent 1, use of the more bulky t-butyldiphenylsilyl group exhibits the highest enantioselectivity. The conformational analysis of two possible chairlike transition-state structures of an allyl vinyl ether substrate reveals that a chiral organoaluminum reagent 1 can discriminate between these two conformations only by a difference in the orientation of α-methylene groups of ethers.

Spermicidal substituted 1-(cycloalkyl)alkylimidazoles

New compounds of the formula STR1 wherein: R1 is cycloalkyl of five to seven carbon atoms optionally substituted with one or more lower alkyl groups; R2 is alkyl of two to twelve carbon atoms, cycloalkyl of five to seven carbon atoms