284663-48-5

Basic information

• Product Name: N,N-dimethyl 2-(p-methoxyphenyl)-3-(trans-2-methoxycarbonylethenyl)-4-trimethylsilyl-1H-pyrrole-1-sulfonamide
• Synonyms: N,N-dimethyl 2-(p-methoxyphenyl)-3-(trans-2-methoxycarbonylethenyl)-4-trimethylsilyl-1H-pyrrole-1-sulfonamide
• CAS NO: 284663-48-5
• Molecular Weight: 436.604
• Mol File: 284663-48-5.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: N,N-dimethyl 2-(p-methoxyphenyl)-3-(trans-2-methoxycarbonylethenyl)-4-trimethylsilyl-1H-pyrrole-1-sulfonamide(CAS DataBase Reference)
• NIST Chemistry Reference: N,N-dimethyl 2-(p-methoxyphenyl)-3-(trans-2-methoxycarbonylethenyl)-4-trimethylsilyl-1H-pyrrole-1-sulfonamide(284663-48-5)
• EPA Substance Registry System: N,N-dimethyl 2-(p-methoxyphenyl)-3-(trans-2-methoxycarbonylethenyl)-4-trimethylsilyl-1H-pyrrole-1-sulfonamide(284663-48-5)

Safety Data

• Hazardous Substances Data: 284663-48-5(Hazardous Substances Data)

Upstream product

• 284663-46-3 N,N-dimethyl 2,4-bis(trimethylsilyl)-3-(trans-2-methoxycarbonylethenyl)-1H-pyrrole-1-sulfonamide 
• 284663-67-8 N,N-dimethyl 2,4-bis(trimethylsilyl)-3-bromo-1H-pyrrole-1-sulfonamide 
• 5720-07-0 4-methoxyphenylboronic acid 
• 284663-47-4 N,N-dimethyl 2-iodo-3-(trans-2-methoxycarbonylethenyl)-4-trimethylsilyl-1H-pyrrole-1-sulfonamide 

Downstream Products

• 284663-51-0 2-(p-methoxyphenyl)-3-(trans-2-methoxycarbonylethenyl)-4-iodo-1H-pyrrole 
• 284663-49-6 N,N-dimethyl 2-(p-methoxyphenyl)-3-(trans-2-methoxycarbonylethenyl)-4-iodo-1H-pyrrole-1-sulfonamide 

Relevant articles and documents

Highly regioselective synthesis of 2,3,4-trisubstituted 1H-pyrroles: A formal total synthesis of lukianol A

A combined use of α-lithiation and nucleophilic substitutions of N,N- dimethyl 3,4-bis(trimethylsilyl)-1H-pyrrole-1-sulfonamide 8c led to several 2-substituted 3,4-bis(trimethylsilyl)-1H-pyrrole-1-sulfonamides. Utilizing the β-effect of a trimethylsilyl group, a highly regioselective synthesis of 2,3,4-trisubstituted 1H-pyrroles 23 and 34 was accomplished. The marine natural product lukianol A (3) was prepared utilizing this strategy.