285138-81-0

Usage

Uses

Used in Agricultural Industry:
CHLORPYRIFOS D10 is used as an insecticide for controlling pests such as termites, ants, and other insects in agricultural settings. Its application helps protect crops from damage caused by these pests, ensuring a stable food supply.
However, due to concerns about its potential toxicity to humans and the environment, regulatory restrictions and bans have been imposed in some countries. Consequently, there is a growing interest in seeking alternative, sustainable pest control practices to replace chlorpyrifos-based pesticides.

InChI:InChI=1/C9H11Cl3NO3PS/c1-3-14-17(18,15-4-2)16-9-7(11)5-6(10)8(12)13-9/h5H,3-4H2,1-2H3/i1D3,2D3,3D2,4D2

Upstream product

• 1516-08-1 ethanol-d6 
• 6515-38-4 3,5,6-trichloropyridin-2 ol 
• 287397-89-1 diethyl chlorothiophosphate-d10 

Relevant academic research and scientific papers

Stable isotope-labeled chlorpyrifos-d10 and synthesis method thereof

The invention discloses stable isotope-labeled chlorpyrifos-d10 and a synthesis method thereof. The synthesis method includes the steps: making stable isotope labeled ethyl alcohol-d10 as a stable isotope labeling source react with phosphorus pentasulfide to obtain stable isotope-labeled o, o-diethylphosphorothioate, making the stable isotope-labeled o, o-diethylphosphorothioate and 3, 5, 6-trichloro-2-pyridinol sodium salt undergo a condensation reaction to obtain the stable isotope labeled chlorpyrifos-d10 product. The stable isotope labeling raw material used in the method is ethanol-d10, the source is easy to obtain, the price is low, the synthesis process is simple and easy to operate, the product is simple and convenient to separate and purify, the chemical purity and isotope abundance of the obtained product can reach 98% or above, and the related requirements of a standard reagent for quantitatively detecting the chlorpyrifos content are met.

Stable isotope-labeled chlorpyrifos and derivative and synthetic preparation method thereof

The invention discloses stable isotope-labeled chlorpyrifos and a derivative and synthetic preparation method thereof. An organic synthesis method is utilized, thiophosphoryl chloride is adopted as araw material, a reaction is performed on a stable isotope-labeled 3,5,6-trichloropyridine-2-ol sodium salt, and then a reaction is performed on the reaction product and stable isotope-labeled short-chain alcohol so as to obtain the stable isotope-labeled chlorpyrifos and the derivative of the stable isotope-labeled chlorpyrifos. After simple separation and purification are performed on the prepared stable isotope-labeled chlorpyrifos and the derivative, the chemical purity can reach 99% or above, and the isotope abundance can reach 99% or above; and the stable isotope-labeled chlorpyrifos andthe derivative can be applied to biological metabolism, food safety, environmental monitoring and other fields, and compared with foreign products, the stable isotope-labeled chlorpyrifos and the derivative have the advantages of good quality and low cost.