28538-67-2

Basic information

• Product Name: 1-methyl-4-phenyl-1,2,4-triazolidine-3,5-dionato
• CAS NO: 28538-67-2
• Molecular Formula: C₉H₉N₃O₂
• Molecular Weight: 191.1867
• Mol File: 28538-67-2.mol
• Article Data: 5

Chemical Properties

• Density: 1.327g/cm³
• Refractive Index: 1.597
• CAS DataBase Reference: 1-methyl-4-phenyl-1,2,4-triazolidine-3,5-dionato(CAS DataBase Reference)
• NIST Chemistry Reference: 1-methyl-4-phenyl-1,2,4-triazolidine-3,5-dionato(28538-67-2)
• EPA Substance Registry System: 1-methyl-4-phenyl-1,2,4-triazolidine-3,5-dionato(28538-67-2)

Safety Data

• Hazardous Substances Data: 28538-67-2(Hazardous Substances Data)

Upstream product

• 103-71-9 phenyl isocyanate 
• 34771-21-6 1-Ethoxycarbonyl-2-methyl-4-phenylsemicarbazid 
• 15988-11-1 4-Phenylurazole 
• 74-88-4 methyl iodide 
• 75-44-5 phosgene 
• 19102-24-0 2-methyl-4-phenyl semicarbazide 
• 60-34-4 methylhydrazine 

Relevant articles and documents

1-Methyl-4-aryl-urazole (MAUra) labels tyrosine in proximity to ruthenium photocatalysts

We designed and synthesised peptides conjugated with proline linkers and ruthenium photocatalysts. These peptides were used as substrates to evaluate the photocatalyst-proximity dependences of candidates for tyrosine labelling reagents. The 1-methyl-4-aryl-urazole (MAUra) structure was found to be a novel tyrosyl radical trapping agent to label tyrosine residues effectively under the conditions where the ruthenium photocatalyst and tyrosine were in close proximity. Using a ruthenium photocatalyst conjugated to a carbonic anhydrase ligand, the target protein in a complex protein mixture was labelled with remarkable target selectivity by azide- or desthiobiotin-conjugated MAUra derivatives.

Carbimide and carbonyl cyclisations of semicarbazides

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Ene Reaction of Triazolinediones with Alkenes. 2. Kinetics and Substituent Effects

The kinetic measurements for the reaction of 4-substituted-1,2,4-triazoline-3,5-diones (4-R-TD; R=Ph, Me, p-MeOC6H4, p-NO2C6H4) with alkenes have been undertaken.The reactivity of alkenes was found to be very sensitive to substituent effects.The effects of solvent and substituent on TD were small.In the reaction of TD with ene products, side reactions as well as second-step ene reactions were observed.The reactions of 1-alkyl-4-phenyl-1,2,4-triazolidine-3,5-diones were investigated, and the reaction products were isolated.