2854-14-0

Upstream product

• 54888-03-8 5-chloro-2-(aceturoylmethylamino)benzophenone 
• 108-24-7 acetic anhydride 
• 5220-02-0 3-amino-6-chloro-1,2-dihydro-1-methyl-2-oxo-4-phenylquinoline 
• 1022-13-5 5-chloro-2-(methylamino)benzophenone 
• 5220-83-7 3-amino-6-chloro-1,2-dihydro-2-oxo-4-phenylquinoline 
• 186581-53-3 diazomethane 
• 548446-45-3 2-acetamido-2-acetoxy-6-chloro-4-phenyl-quinoline 

Relevant academic research and scientific papers

Chemical transformations of 3-amino-2-quinolones

In order to find new antimalarial drugs, an exploration about the chemical properties of the starting compounds 3-amino-6-chloro-4-phenyl-1H-quinolin-2-one (1) and 3-amino-4-methyl-1H-quinolin-2-one (2) was developed. Acylation with acyl chloride, sulfony

New Synthesis of Diazepam

An efficient preparation of 7-chloro-1-methyl-3,4-dihydro-1H-1,4-benzodiazepine-2,5-dione from 5-chloro-N-methylisatoic anhydride and glycine has been devised, and from it, by the action of phenylmagnesium chloride on its N-acetyl-derivative followed by treatment with hydroxylamine and cleavage of the resulting desacetyl oxime with sodium bisulfite, diazepam has been synthesized.The overall yield is about 50percent from 5-chloroisatoic anhydride.