Welcome to LookChem.com Sign In|Join Free

CAS

  • or

5220-02-0

DIAZEPAM RELATED COMPOUND B (25 MG) (3-AMINO-6-CHLORO-1-METHYL-4-PHENYLCARBOSTYRIL) is a chemical compound that is identified as an impurity in the synthesis of Diazepam, a well-known anxiolytic, muscle relaxant, and anticonvulsant medication. DIAZEPAM RELATED COMPOUND B (25 MG) (3-AMINO-6-CHLORO-1-METHYL-4-PHENYLCARBOSTYRIL) is characterized by its molecular structure, which includes an amino group, a chloro substituent, and a methyl group attached to a phenylcarbostyril backbone.

5220-02-0 Suppliers

Post Buying Request

Recommended suppliersmore

  • Product
  • FOB Price
  • Min.Order
  • Supply Ability
  • Supplier
  • Contact Supplier
  • 5220-02-0 Structure

  • Basic information

    1. Product Name: DIAZEPAM RELATED COMPOUND B (25 MG) (3-AMINO-6-CHLORO-1-METHYL-4-PHENYLCARBOSTYRIL)
    2. Synonyms: 3-Amino-6-chloro-1-methyl-4-phenylquinolin-2(1H)-one;6-Chloro-4-phenyl-1-methyl-3-aminoquinoline-2(1H)-one;DiazepaM Related CoMpound B;3-Amino-6-chloro-1-methyl-4-phenyl-2(1H)-quinolinone;3-Amino-6-chloro-1-methyl-4-phenylcarbostyril;3-Amino-1,2-dihydro-6-chloro-1-methyl-4-phenylquinolin-2(1H)-one;DIAZEPAM RELATED COMPOUND B (25 MG) (3-AMINO-6-CHLORO-1-METHYL-4-PHENYLCARBOSTYRIL);3-amino-6-chloro-1-methyl-4-phenyl-2(1h)-quinolinon
    3. CAS NO:5220-02-0
    4. Molecular Formula: C16H13ClN2O
    5. Molecular Weight: 284.74022
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 5220-02-0.mol

  • Chemical Properties

    1. Melting Point: 130-133 °C
    2. Boiling Point: 436.3°Cat760mmHg
    3. Flash Point: 217.7°C
    4. Appearance: /
    5. Density: 1.313g/cm3
    6. Vapor Pressure: 8.18E-08mmHg at 25°C
    7. Refractive Index: 1.652
    8. Storage Temp.: N/A
    9. Solubility: N/A
    10. PKA: 3.14±0.20(Predicted)
    11. CAS DataBase Reference: DIAZEPAM RELATED COMPOUND B (25 MG) (3-AMINO-6-CHLORO-1-METHYL-4-PHENYLCARBOSTYRIL)(CAS DataBase Reference)
    12. NIST Chemistry Reference: DIAZEPAM RELATED COMPOUND B (25 MG) (3-AMINO-6-CHLORO-1-METHYL-4-PHENYLCARBOSTYRIL)(5220-02-0)
    13. EPA Substance Registry System: DIAZEPAM RELATED COMPOUND B (25 MG) (3-AMINO-6-CHLORO-1-METHYL-4-PHENYLCARBOSTYRIL)(5220-02-0)

  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 5220-02-0(Hazardous Substances Data)

5220-02-0 Usage

Uses

Used in Pharmaceutical Industry:
DIAZEPAM RELATED COMPOUND B (25 MG) (3-AMINO-6-CHLORO-1-METHYL-4-PHENYLCARBOSTYRIL) is used as an impurity in the synthesis of Diazepam (D416855) for the following reasons:
1. As an anxiolytic: It contributes to the development of medications that help alleviate anxiety and stress-related disorders.
2. As a muscle relaxant (skeletal): It plays a role in the creation of drugs that can help relax skeletal muscles, providing relief from muscle spasms and pain.
3. As an anticonvulsant: It is involved in the synthesis of medications that help prevent and control seizures, offering support to individuals with epilepsy and other seizure disorders.

Synthesis Reference(s)

The Journal of Organic Chemistry, 38, p. 449, 1973 DOI: 10.1021/jo00943a008

Check Digit Verification of cas no

The CAS Registry Mumber 5220-02-0 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 5,2,2 and 0 respectively; the second part has 2 digits, 0 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 5220-02:
(6*5)+(5*2)+(4*2)+(3*0)+(2*0)+(1*2)=50
50 % 10 = 0
So 5220-02-0 is a valid CAS Registry Number.
InChI:InChI=1/C16H13ClN2O/c1-19-13-8-7-11(17)9-12(13)14(15(18)16(19)20)10-5-3-2-4-6-10/h2-9H,18H2,1H3

5220-02-0 Well-known Company Product Price

  • Brand
  • (Code)Product description
  • CAS number
  • Packaging
  • Price
  • Detail

  • USP

  • (1023403)  Diazepam Related Compound B  United States Pharmacopeia (USP) Reference Standard

  • 5220-02-0

  • 1023403-25MG

  • 14,578.20CNY

  • Detail

5220-02-0SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 18, 2017

Revision Date: Aug 18, 2017

1.Identification

1.1 GHS Product identifier

Product name 3-amino-6-chloro-1-methyl-4-phenylquinolin-2-one

1.2 Other means of identification

Product number -
Other names Diazepam Related Compound B

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:5220-02-0 SDS

5220-02-0Relevant articles and documents

Chemical transformations of 3-amino-2-quinolones

Asis, Silvia E.,Bruno, Ana M.,Dominici, Diego A.,Bollini, Mariela,Gaozza, Carlos H.

, p. 107 - 112 (2007/10/03)

In order to find new antimalarial drugs, an exploration about the chemical properties of the starting compounds 3-amino-6-chloro-4-phenyl-1H-quinolin-2-one (1) and 3-amino-4-methyl-1H-quinolin-2-one (2) was developed. Acylation with acyl chloride, sulfony

Synthesis of Pyridinium Heterocyclic Ylides. Degradation of the Pyridinium Group

Esteve, Marta E.,Gaozza, Carlos H.

, p. 1061 - 1063 (2007/10/02)

The synthesis of pyridinium-quinolone chlorides and ylides, a pyridinium-methylquinazolone ylide, 9-pyridinium acridine chloride, and their behaviour by treatment by boiling aniline are described.

New Synthesis of Diazepam

Gates, Marshall

, p. 1675 - 1681 (2007/10/02)

An efficient preparation of 7-chloro-1-methyl-3,4-dihydro-1H-1,4-benzodiazepine-2,5-dione from 5-chloro-N-methylisatoic anhydride and glycine has been devised, and from it, by the action of phenylmagnesium chloride on its N-acetyl-derivative followed by treatment with hydroxylamine and cleavage of the resulting desacetyl oxime with sodium bisulfite, diazepam has been synthesized.The overall yield is about 50percent from 5-chloroisatoic anhydride.

Post a RFQ

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

1

What can I do for you?
Get Best Price

Get Best Price for 5220-02-0