28544-77-6

Usage

Uses

Used in Pharmaceutical and Agrochemical Industries:
Pyridazine-3-thiol is utilized as a key building block in the synthesis of various pharmaceuticals and agrochemicals, owing to its unique chemical structure and properties that can be tailored for specific therapeutic or pesticidal effects.
Used in Organic Synthesis:
As an intermediate in organic synthesis, Pyridazine-3-thiol is employed for the creation of complex organic molecules, leveraging its reactive sites for the formation of new chemical entities.
Used in Materials Science:
Pyridazine-3-thiol is used as a component in the development of corrosion inhibitors, where its chemical properties can provide protective coatings against environmental degradation of materials.
Pyridazine-3-thiol is also used in the research and development of electroactive materials, where its electronic properties can be harnessed for applications in sensors, batteries, or other electronic devices.
Used in Antimicrobial Applications:
Pyridazine-3-thiol is employed as an antimicrobial agent, leveraging its potential antibacterial and antifungal properties to combat microbial infections in various settings.
Used in Antitumor Research:
In the field of oncology, Pyridazine-3-thiol is studied for its antitumor properties, with the aim of developing new therapeutic agents for the treatment of cancer.

InChI:InChI=1/C4H4N2S/c7-4-2-1-3-5-6-4/h1-3H,(H,6,7)

Upstream product

• 504-30-3 2H-Pyridazin-3-one 
• 504-30-3 3-hydroxypyridazine 
• 1120-95-2 3-chloropyridazine 

Downstream Products

• 21948-71-0 3-(methylthio)pyridazine 
• 159172-50-6 N-cyclohexyl-3-pyridazine sulfenamide 

Relevant academic research and scientific papers

PARP INHIBITORS

The present application disclosed compounds of Formula I wherein variables R1 and R2 are defined as described herein, which are inhibitors of PARP and provides compounds and compositions containing the compounds of Formula I. The pre

GAMMA SECRETASE INHIBITORS

Disclosed herein are compounds of Formula (I) (I) and pharmaceutically acceptable salts thereof, wherein each of the substituents is given the definition as set forth in the specification and claims. Also disclosed are pharmaceutical compositions containi

6-SUBSTITUTED- 2,3,4,5-TETRAHYDRO-1H-BENZO[D]AZEPINES AS 5-HT2C RECEPTOR AGONISTS

The present invention provides 6-substituted 2,3,4,5-tetrahydro-lH- benzo[d]azepines of Formula (I) as selective 5-HT2C receptor agonists for the treatment of 5-HT2c associated disorders including obesity, obsessive/compulsive disorder, depression, and anxiety: R6 D R? N-R" R* where R6 is -(CrC3)alkyl-S-(C0-C3)alkyl-R10, -(C1-C3)alkyl-NR11R12, -(CrC3)alkyl-O- R 13. and other substituents are as defined in the specification.

Theoretical and Infrared Matrix Isolation Study of 4(3H)-Pyrimidinethione and 3(2H)-Pyridazinethione. Tautomerism and Phototautomerism

IR spectra of 4(3H)-pyrimidinethione and 3(2H)-pyridazinethione isolated in argon and nitrogen matrices are reported.The thiol and thione tautomeric forms of 4(3H)-pyrimidinethione were found in matrices in relative concentrations ca. 5:1.IR spectra of gaseous sample showed that the ratio of tautomers in matrices corresponds to the gas-phase tautomeric equilibrium.Only the thione form of 3(2H)-pyridazinethione was observed in matrices.UV-vis irradiation of the matrices caused the conversion ot the thione forms of the studied molecules into the thiol forms.The IR spectra of the thione and thiol tautomers were predicted theoretically a t SCF/3-21G* level, and a comparison ot the predicted and experimentally observed spectra enabled an assignment of most of the observed bands.

Cephalosporin displacement reaction

The present invention is directed to a process for the displacement of the acetoxy group of a cephalosporanic acid by a sulfur nucleophile, in an organic solvent and under essentially anhydrous conditions.

7-(3-Substituted ureido) cephalosporins

Cephalosporin compounds with 3-substituted ureido or -thioureido group at position 7 and hydrogen or heterocyclicthiomethyl groups at position 3 are prepared. These compounds are antibacterial agents.