285980-95-2 Usage
Chemical Class
Thieno[2,3-b]pyridine
Explanation
The compound belongs to the thieno[2,3-b]pyridine class, which is a group of organic compounds containing a fused pyridine and thiophene ring system.
Explanation
The compound contains a thienyl group, which is a five-membered aromatic ring with one sulfur atom, attached at the 6th position of the thieno[2,3-b]pyridine core.
Explanation
The compound has an amino group (-NH2) attached at the 3rd position of the thieno[2,3-b]pyridine core, which can participate in various chemical reactions and interactions.
Explanation
The compound features a trifluoromethyl group (-CF3) at the 4th position of the thieno[2,3-b]pyridine core, which can influence the compound's lipophilicity and reactivity.
Explanation
The compound has an ethanone (keto) group (-CO-CH3) attached to the 1st position of the thieno[2,3-b]pyridine core, which can be involved in hydrogen bonding and other interactions.
Explanation
Due to its unique structure, the compound may exhibit biological activity and could be used in the development of new drugs or as a starting point for further chemical modifications.
Explanation
The specific properties, uses, and potential applications of the compound would need to be explored through additional research and experimentation to fully understand its potential in medicinal chemistry and drug development.
Thienyl Group
6-(2-Thienyl)
Amino Group
3-Amino
Trifluoromethyl Group
4-(Trifluoromethyl)
Ethanone Moiety
1-Ethanone
Potential Applications
Medicinal Chemistry and Drug Development
Further Investigation
Research and Experimentation
Check Digit Verification of cas no
The CAS Registry Mumber 285980-95-2 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 2,8,5,9,8 and 0 respectively; the second part has 2 digits, 9 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 285980-95:
(8*2)+(7*8)+(6*5)+(5*9)+(4*8)+(3*0)+(2*9)+(1*5)=202
202 % 10 = 2
So 285980-95-2 is a valid CAS Registry Number.
InChI:InChI=1/C14H9F3N2OS2/c1-6(20)12-11(18)10-7(14(15,16)17)5-8(19-13(10)22-12)9-3-2-4-21-9/h2-5H,18H2,1H3
285980-95-2Relevant academic research and scientific papers
Synthesis and reactions of 4-trifluoromethyl-3-cyano pyridine-2(1H)-thione/ one derivatives
Rateb, Nora M.
, p. 611 - 622 (2012/05/04)
4,4,4-Trifluoro-1-(thiophen-2-yl)butane-1,3-dione was reacted by grinding with cyanothioacetamide and cyanoacetamide under solvent-free conditions at 25°C to give pyridine-2(1H)thione/one derivatives in excellent yields. These compounds were further reacted by grinding with different halogenated reagents to give 2-S/O-alkyl pyridine derivatives. The latter compounds were utilized for the synthesis of thieno[2,3-b]pyridine, pyrazolopyridine, pyridothienopyrimidine and pyridothienooxazinone derivatives.
Fluorine-containing heterocycles: Synthesis and some reactions of new 3-amino-2-functionalized-6-(2′-thienyl)-4-trifluoromethylthieno [2,3-b]pyridines
Abdel-Monem,Mohamed,Bakhite
, p. 41 - 44 (2007/10/03)
3-Cyano-6-(2′-thienyl)-4-trifluoromethylpyridine-2(1H)-thione (2) was prepared and reacted with chloroacetone or phenacyl bromide to yield the 2-acetyl or benzoyl-3-amino-6-(2′-thienyl)-4-trifluoromethylthieno[2,3-b]pyridines (3a, b). In contrast, the reaction of 2 with chloroacetamide or its N-aryl derivatives gave the corresponding 2-carbamoylmethyl thiopyridines 4a-c. Upon treatment of these educts with K2CO3 or C2H5ONa in ethanol, they underwent intramolecular Thorpe-Ziegler cyclization to afford 3-amino-2-carbamoyl-6-(2′-thienyl)-4-trifluoromethyl-thieno[2,3-b]pyrid ine (5a) and its N-aryl analogs 5b, c. Compounds 5a-c underwent some reactions to yield new pyrido[3',2':4,5]thieno[3,2-d]pyrimidines and pyrido[3′,2′:4,5]thieno[3,2-d][1,2,3] triazines.
