286-22-6

Usage

Uses

Used in Pharmaceutical Industry:
3,7-Dioxabicyclo[4.1.0]heptane is used as a solvent and humectant for various pharmaceutical applications. Its ability to retain moisture makes it suitable for use in formulations of topical medications, such as creams and ointments, to maintain the hydration of the skin.
Used in Food Industry:
In the food industry, 3,7-Dioxabicyclo[4.1.0]heptane is used as a humectant to retain moisture in food products, such as baked goods, confectionery, and pet food. It helps to maintain the texture and freshness of these products.
Used in Cosmetics Industry:
3,7-Dioxabicyclo[4.1.0]heptane is used as a moisturizing agent in cosmetics and personal care products. Its hygroscopic properties help to keep the skin hydrated and maintain its natural moisture balance.
Used in Industrial Applications:
3,7-Dioxabicyclo[4.1.0]heptane is used as a component in the production of various industrial products, such as resins, plastics, and inks. Its versatility as a solvent and its ability to form stable emulsions make it a valuable ingredient in these applications.
Used in Energy Industry:
3,7-Dioxabicyclo[4.1.0]heptane is used as a feedstock in the production of biofuels, such as biodiesel. Its ability to be derived from renewable resources, like plant oils, makes it a sustainable alternative to fossil fuels.

Upstream product

• 134419-59-3 4-oxanyl methanesulfonate 
• 2081-44-9 Tetrahydro-pyran-4-ol 
• 3174-74-1 dihydropyran 
• 25637-16-5 4-bromotetrahydro-2H-pyran 

Downstream Products

• 872360-02-6 8-(3-hydroxy-tetrahydro-pyran-4-yl)-1-phenyl-1,3,8-triaza-spiro[4.5]decan-4-one 
• 872360-01-5 8-(4-hydroxy-tetrahydro-pyran-3-yl)-1-phenyl-1,3,8-triaza-spiro[4.5]decan-4-one 
• 445480-33-1 tert-butyl [(3R,4S)-3-hydroxytetrahydro-2H-pyran-4-yl]carbamate 
• 1630815-44-9 trans-4-amino-3-hydroxytetrahydropyran hydrochloride 
• 1096594-11-4 3-amino-1,5-anhydro-2,3-dideoxy-L-threo-pentitol hydrochloride 
• 1363380-59-9 trans-4-aminotetrahydro-2H-pyran-3-ol 
• 851338-89-1 rac-8-(4-oxo-tetrahydro-pyran-3-yl)-1-phenyl-1,3,8-triaza-spiro[4.5]decan-4-one 
• 851338-92-6 rac-8-(3-oxo-tetrahydro-pyran-4-yl)-1-phenyl-1,3,8-triaza-spiro[4.5]decan-4-one 
• 1309081-45-5 (3S,4S)-3-aminotetrahydro-2H-pyran-4-ol 

Relevant academic research and scientific papers

Selective Isomerization via Transient Thermodynamic Control: Dynamic Epimerization of trans to cis Diols

Traditional approaches to stereoselective synthesis require high levels of enantio- and diastereocontrol in every step that forms a new stereocenter. Here, we report an alternative approach, in which the stereochemistry of organic substrates is selectivel

PEPTIDE CONJUGATES OF CYTOTOXINS AS THERAPEUTICS

The present invention relates to peptide conjugates of cytotoxins such as topoisomerase I inhibitors which are useful for the treatment of diseases such as cancer.

6-HETEROARYLOXY BENZIMIDAZOLES AND AZABENZIMIDAZOLES AS JAK2 INHIBITORS

The present disclosure provides 6-heteroaryloxy benzimidazole and azabenzimidazole compounds and compositions thereof useful for inhibiting JAK2.

ANTI-INFLAMMATORY COMPOSITIONS COMPRISING IRAK AND JAK INHIBITORS

The present invention discloses compositions comprising compounds according to Formula I wherein R1, R2, and Cy are as defined herein, and a second compound having a JAK inhibiting activity. The present invention relates to composition, methods for their production, pharmaceutical compositions comprising the same, and methods of treatment using the same, for the prophylaxis and/or treatment of inflammatory diseases, autoimmune diseases, proliferative diseases, allergic diseases, transplant rejection, diseases involving impairment of cartilage turnover, congenital cartilage malformations, and/or diseases associated with hypersecretion of IL6 or interferons by administering the compound of the invention

6-[5-AMINO-6-(2-ETHOXYETHOXY)-IMIDAZO[4,5-B]PYRIDIN-3-YL]-NICOTINONITRILE DERIVATIVES AND THEIR USE AS IRAK INHIBITORS

The present invention discloses compounds according to Formula (I): wherein R1, R2, and Cy are as defined herein. The present invention relates to compounds inhibiting IRAK family kinases, methods for their production, pharmaceutical compositions comprising the same, and methods of treatment using the same, for the prophylaxis and/or treatment of inflammatory diseases, autoimmune diseases and/or proliferative diseases by administering the compound of the invention.

FLOURO-NAPHTHYL DERIVATIVES

The present invention relates to compounds of formula wherein R1 is C4-6-cycloalkyl or C4-6-heterocycloalkyl, which are optionally substituted by one or two substituents, selected from hydroxy or lower alkyl; A is phenyl, pyridinyl or piperidinyl; R2 is hydrogen, halogen, lower alkyl, cyano, C4-6-cycloalkyl, lower alkoxy, lower alkoxy substituted by halogen, or is a five- or six-membered heteroaryl, optionally substituted by lower alkyl; n is 1 or 2; or to a pharmaceutically acceptable acid addition salt, to a racemic mixture or to its corresponding enantiomer and/or optical isomers thereof. The compounds may be used for the treatment or prophylaxis of Alzheimer's disease, cognitive impairment, schizophrenia, pain or sleep disorders.

SUBSTITUTED PYRIDINES AND METHOD OF USE

The invention discloses compounds of Formula (I) wherein X, R1, R2, and R3 are as defined herein. The present invention relates to compounds and their use in the treatment of cystic fibrosis, methods for their production, pharmaceutical compositions comprising the same, and methods of treating cystic fibrosis by administering a compound of the invention.

SELECTIVE ANDROGEN RECEPTOR MODULATORS

The present invention provides novel selective androgen receptor modulators and their salts and pharmaceutical compositions thereof.

SELECTIVE KINASE INHIBITORS

Provided are pyrimidine compounds for inhibiting of Syk kinase, intermediates used in making such compounds, methods for their preparation, pharmaceutical compositions thereof, methods for inhibition Syk kinase activity, and methods for treating conditions mediated at least in part by Syk kinase activity.

SUBSTITUTED CYCLIC COMPOUNDS AND METHODS OF USE

The present invention provides novel substituted cyclic compounds, pharmaceutical acceptable salts and formulations thereof useful in modulating the protein tyrosine kinase activity, and in modulating cellular activities such as proliferation, differentiation, apoptosis, migration and invasion. The invention also provides pharmaceutically acceptable compositions comprising such compounds and methods of using the compositions in the treatment of hyperproliferative disorders in mammals, especially humans.