28619-26-3Relevant articles and documents
Multiplex detection of enzymatic activity with responsive lanthanide-based luminescent probes
Pershagen, Elias,Borbas, K. Eszter
supporting information, p. 1787 - 1790 (2015/02/19)
Multiplex analyte detection in complex dynamic systems is desirable for the investigation of cellular communication networks as well as in medical diagnostics. A family of lanthanide-based responsive luminescent probes for multiplex detection is reported. The high modularity of the probe design enabled the rapid assembly of both green and red emitters for a large variety of analytes by the simple exchange of the lanthanide or an analyte-cleavable caging group, respectively. The real-time three-color detection of up to three analytes was demonstrated, thus setting the stage for the non-invasive investigation of interconnected biological processes. © 2015 Wiley-VCH Verlag GmbH & Co. KGaA , Weinheim.
Cysteine-based mannoside glycoclusters: Synthetic routes and antiadhesive properties
Schierholt, Alexander,Hartmann, Mirja,Schwekendiek, Kirsten,Lindhorst, Thisbe K.
experimental part, p. 3120 - 3128 (2010/08/19)
Clustermannosides of different valency were synthesised based on cysteine. By employing the orthogonally protected amino acid as scaffold molecule, a variety of structurally varied products can be obtained according to different synthetic routes. Testing of the prepared glycoclusters as inhibitors of type 1 fimbriae mediated bacterial adhesion is reported, giving hints about the influence of sugar valency, sugar scaffolding, and the nature of the glycosidic aglycon in this testing system.
Glycosylated prodrugs, their method of preparation and their uses
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, (2008/06/13)
Glycosylated prodrugs, a preparation method therefor, and their use with tumor-specific immunoenzymatic conjugates for the treatment of cancer, are described. These anthracycline prodrugs have formula (I). STR1