2866-71-9

Basic information

• Product Name: [1,1'-Bicyclopentyl]-2-one, (S)-
• CAS NO: 2866-71-9
• Molecular Formula: C10H16O
• Molecular Weight: 152.236
• Mol File: 2866-71-9.mol
• Article Data: 14

Chemical Properties

• CAS DataBase Reference: [1,1'-Bicyclopentyl]-2-one, (S)-(CAS DataBase Reference)
• NIST Chemistry Reference: [1,1'-Bicyclopentyl]-2-one, (S)-(2866-71-9)
• EPA Substance Registry System: [1,1'-Bicyclopentyl]-2-one, (S)-(2866-71-9)

Safety Data

• Hazardous Substances Data: 2866-71-9(Hazardous Substances Data)

Usage

General Description

[1,1'-Bicyclopentyl]-2-one, (S)- is a chemical compound known for its bicyclic structure and its chirality, with the "S" configuration indicating that the molecule has a specific orientation in space. It is commonly used as a chiral building block in organic synthesis, and its unique structure makes it an important intermediate in the production of various pharmaceuticals and other fine chemicals. The compound has high purity and is stable under normal conditions, making it a valuable tool for researchers and chemists working in the field of organic chemistry and drug development.

Upstream product

• 120-92-3 cyclopentanone 
• 4884-21-3 1-cyclopentyl-cyclopentene 
• 930-30-3 cyclopent-2-enone 
• 96-41-3 Cyclopentanol 
• 124-04-9 Adipic acid 
• 825-25-2 2-cyclopentylidenecyclopentan-1-one 
• 123-91-1 1,4-dioxane 
• 142-29-0 cyclopentene 
• 137629-11-9 (1SR,5RS,7SR)-7-(3'-bromopropyl)bicyclo<3.2.0>heptan-6-one 
• 5181-75-9 bicyclopentyl-1,1'-diol 
• 4884-25-7 2-cyclopentylcyclopentanol 

Downstream Products

• 3835-64-1 2,2-dimethyl-1-phenylpropan-1-ol 
• 4884-25-7 2-cyclopentylcyclopentanol 
• 89-78-1 2-isopropyl-5-methylcyclohexan-1-ol 
• 16429-17-7 6-cyclopentylvalerolactone 
• 1636-39-1 bicyclopentyl 
• 101747-12-0 (+/-)-1-cyclopentyl-3-(benzylidene-(seqtrans))-cyclopentanone-⁽²⁾ 
• 687996-16-3 cis-2-Cyclopentyl-cyclopentylamin 
• 704209-22-3 (1R,2R)-bicyclopentyl-2-ylamine 
• 102707-14-2 N-bicyclopentyl-2-yl-N-butyl-N'-phenyl-urea 
• 2862-71-7 (+/-)-1r-cyclopentyl-cyclopentanol-(2c) 
• 2862-71-7 (+/-)-1r-cyclopentyl-cyclopentanol-(2t) 

Relevant articles and documents

Fine-Bubble-Slug-Flow Hydrogenation of Multiple Bonds and Phenols

We describe a promising method for the continuous hydrogenation of alkenes or alkynes by using a newly developed fine-bubble generator. The fine-bubble-containing slug-flow system was up to 1.4 times more efficient than a conventional slug-flow method. When applied in the hydrogenation of phenols to the corresponding cyclohexanones, the fine bubble-slug-flow method suppressed over-reduction. As this method does not require the use of excess gas, it is expected to be widely applicable in improving the efficiency of gas-mediated flow reactions.

The identification of 7-[(R)-2-((1S,2S)-2-benzyloxycyclopentylamino)-1- hydroxyethyl]-4-hydroxybenzothiazolone as an inhaled long-acting β2-adrenoceptor agonist

The optimisation of two series of 4-hydroxybenzothiazolone derived β2-adrenoceptor agonists, bearing α-substituted cyclopentyl and β-phenethyl amino-substituents, as inhaled long-acting bronchodilators is described. Analogues were selected for synthesis using a lipophilicity based hypothesis to achieve the targeted rapid onset of action in combination with a long duration of action. The profiling of the two series led to identification of the α-substituted cyclopentyl analogue 2 as the optimal compound with a comparable profile to the inhaled once-daily long-acting β2-adrenoceptor agonist indacaterol. On the basis of these data 2 was promoted as the backup development candidate to indacaterol from the Novartis LABA project.

Synthesis of renewable high-density fuels using cyclopentanone derived from lignocellulose

By the combination of solvent-free aldol condensation and one-step hydrodeoxygenation under mild reaction conditions, a high-density (0.866 g mL-1) bicyclic C10 hydrocarbon was synthesized in high overall yield (up to 80%) using cyclopentanone derived from lignocellulose. The Royal Society of Chemistry 2014.