286932-63-6Relevant academic research and scientific papers
AGRICULTURAL CHEMICALS
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Page/Page column 59; 109, (2019/08/08)
The present invention relates to picolinic acid derivatives that are useful in treating fungal diseases ofplants.
A focused library of protein tyrosine phosphatase inhibitors
Comeau, Anthony B.,Critton, David A.,Page, Rebecca,Seto, Christopher T.
supporting information; experimental part, p. 6768 - 6772 (2010/11/18)
Protein tyrosine phosphatases such as PTP1B and YopH are potential targets for the development of therapeutic agents against a variety of pathological conditions including diabetes, obesity, and infection by the bacterium Yersinia pestis. A focused library of bidentate α-ketoacid-based inhibitors has been screened against several tyrosine phosphatases. Compound 2a has IC 50 values of 43 and 220 nM against YopH and PTP1B, respectively, and shows a 30-fold selectivity for PTP1B over the closely related phosphatase TCPTP.
Potentiators of glutamate receptors
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Page 31, (2010/02/05)
The present invention relates to potentiators of metabotropic glutamate receptor function and specifically provides compounds of formula I, compositions thereof and methods of using the same.
