28698-47-7Relevant academic research and scientific papers
A cavitand stabilizes the Meisenheimer complex of SNAr reactions
Butterfield, Sara M.,Rebek Jr., Julius
, p. 1605 - 1607 (2007)
A deep cavitand binds amine nucleophiles and accelerates their subsequent SNAr reactions by solvating the intermediate Meisenheimer complex. The Royal Society of Chemistry.
The effects of ring substituents and leaving groups on the kinetics of SNAr reactions of 1-halogeno- and 1-phenoxy-nitrobenzenes with aliphatic amines in acetonitrile
Crampton, Michael R.,Emokpae, Thomas A.,Isanbor, Chukwuemeka
, p. 1378 - 1383 (2008/09/18)
Rate constants are reported for the reactions of a series of 1-chloro-, 1-fluoro- and 1-phenoxy-nitrobenzenes activated by CF3 or CN groups or by ring-nitrogen with n-butylamine, pyrrolidine or piperidine in acetonitrile. The results are compar
The Origins of the Dichotomy of Amine Effects in Aromatic Nucleophilic Substitution Reactions
Akpojivi, Raymond E.,Emokpae, Thomas A.,Hirst, Jack
, p. 443 - 450 (2007/10/02)
The reactions of 2-trifluoromethyl- amd 2-cyano-4-nitrofluoro-benzenes with piperidine, n-butylamine and benzylamine in acetonitrile are not base catalysed, but the reactions with morpholine are catalysed.In benzene, the reactions of the 2-cyano-substrate
