287108-67-2

Upstream product

• 287108-58-1 5-bromo-2-[(4-fluoro-benzenesulfonyl)-methyl-amino]-3-methyl-benzoic acid methyl ester 
• 287108-60-5 5-bromo-2-[(4-hydroxy-benzenesulfonyl)-methyl-amino]-3-methyl-benzoic acid methyl ester 
• 206548-14-3 2-Amino-5-bromo-3-methyl-benzoic acid methyl ester 
• 349-88-2 4-Fluorobenzenesulfonyl chloride 
• 1002-36-4 hep-2-yn-1-ol 

Relevant academic research and scientific papers

ACETYLENIC ARYL SULFONAMIDE AND PHOSPHINIC ACID AMIDE HYDROXAMIC ACID TACE INHIBITORS

Hydroxamic acids having formula (B) wherein the variables are as defined herein, are useful in treating disease conditions mediated by TNF- alpha such as rheumatoid arthritis, osteoarthritis, sepsis, AIDS, ulcerative colitis, multiple sclerosis, Crohn's d

Anthranilate sulfonamide hydroxamate TACE inhibitors. Part 1: Structure-based design of novel acetylenic P1′ groups

The structure-based design of potent sulfonamide hydroxamate TACE inhibitors bearing novel acetylenic P1′ groups has led to compounds with excellent in vitro potency against TACE and selectivity over MMP-1.