28712-36-9Relevant academic research and scientific papers
Ecofriendly synthesis of halogenated flavonoids and evaluation of their antifungal activity
Bernini, Roberta,Pasqualetti, Marcella,Provenzano, Gianfranco,Tempesta, Sabrina
, p. 2980 - 2987 (2015/04/22)
Brominated and chlorinated flavonoids belonging to different classes (flavanones, flavones and catechins) were prepared from the corresponding flavonoids by a simple and ecofriendly procedure based on the use of sodium halides, aqueous hydrogen peroxide and acetic acid. Pure samples of substrates and products were tested against Trichoderma koningii, Fusarium oxysporum and Cladosporium cladosporioides, common saprotrophic soil and seed fungi, potential pathogens for humans and their activity was expressed as linear mycelial growth inhibition (%). Among them, 8-chloro-5,7,3′,4′-tetramethoxyepicatechin 29, a novel catechin derivative, exhibited a remarkable effect against all tested fungi also at low concentrations.
Synthesis of Condensed Tannins. Part 12. Direct Access to - and -all-2,3-cis-Procyanidin Derivatives from (-)-Epicatechin: Assessment of Bonding Positions in Oligomeric Analogues from Crataegus oxyacantha L.
Kolodziej, Herbert,Ferreira, Daneel,Roux, David G.
, p. 343 - 350 (2007/10/02)
Synthesis of methyl ester acetates of - and -all-2,3-cis-procyanidin biflavanoids is effected by oxidative functionalization of (-)-epicatechin tetramethyl ester with lead tetra-acetate, and condensation of the resultant 2,3-cis-flavan-3,4-diol
Tannins and Related Compounds. Part 13. Isolation and Structures of Trimeric, Tetrameric, and Pentameric Proanthicyanidins from Cinnamon
Nonaka, Gen-ichiro,Morimoto, Satoshi,Nishioka, Itsuo
, p. 2139 - 2145 (2007/10/02)
A proanthocyanidin trimer, two tetramers, and a pentamer have been isolated in their free phenolic forms from cinnamon, the bark of Cinnamomum zeylanicum (Lauraceae).Partial acid-catalysed degradation of these tannins with phenylmethanethiol, in conjunction with 1H- and 13C-n.m.r. analysis, has unequivocally established their structures as epicatechin-(4β->8, 2β->7)epicatechin-(4α->8)-epicatechin (5); epicatechin-(4β->8)epicatechin-(4β->8, 2β->7)-epicatechin-(4α->8)-epicatechin (6); epicatechin-(4β->6)-epicatechin-(4β->8, 2β->7)-epicatechin-(4α->8)-epicatechin (7); and epicatechin-(4β->8)-epicatechin-(4β->8)epicatechin-(4β->8, 2β->7)-epicatechin-(4α->8)-epicatechin (8).
