490-46-0

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Basic information

Product Name: L-Epicatechin
Synonyms: (-)-EPICATECHIN;(+)-EPICATECHIN;EPICATECHIN;EPICATECHIN, (-)-;EPICATECHIN, (+)-;CIS-2-[3,4-DIHYDROXYPHENYL]-3,4-DIHYDRO-2H-1-BENZOPYRAN-3,5,7-TRIOL;(-)-CIS-3,3',4',5,7-PENTAHYDROXYFLAVANE;CIS-3,3',4',5,7-PENTAHYDROXYFLAVANE
CAS NO: 490-46-0
Molecular Formula: C15H14O6
Molecular Weight: 290.27
EINECS: 207-710-1
Product Categories: Pharmaceutical Raw Materials;chiral;Aromatics;Chiral Reagents;Inhibitors;Intermediates & Fine Chemicals;Pharmaceuticals;chemical reagent;pharmaceutical intermediate;phytochemical;reference standards from Chinese medicinal herbs (TCM).;standardized herbal extract
Mol File: 490-46-0.mol

Chemical Properties

Melting Point: 240 °C (dec.)(lit.)
Boiling Point: 630.4 °C at 760 mmHg
Flash Point: 335°C
Appearance: White to light yellow crystal powder
Density: 1.593g/cm³
Refractive Index:
Storage Temp.: 2-8°C
Solubility:
Water Solubility: Soluble in water or alcohol
Merck: 13,1912
CAS DataBase Reference: L-Epicatechin(CAS DataBase Reference)
NIST Chemistry Reference: L-Epicatechin(490-46-0)
EPA Substance Registry System: L-Epicatechin(490-46-0)

Safety Data

Hazard Codes: Xi
Statements: 36/37/38
Safety Statements: 26-36
WGK Germany: 3
RTECS: KB3745000
F: 10-23
HazardClass:
PackingGroup:
Hazardous Substances Data: 490-46-0(Hazardous Substances Data)

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SDS
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Product	FOB Price	Min.Order	Supply Ability	Supplier
Epicatechin Cas No: 490-46-0	No Data	1 Gram	5 Metric Ton/Day	CHANGZHOU HANGYU PHARMACEUTICAL TECHNOLOGY CO., LTD	Contact Supplier
L-epicatechin Cas No: 490-46-0	No Data	1 Gram	1 Metric Ton/Month	Health Chemicals Co., Ltd.	Contact Supplier
L-Epicatechin Cas No: 490-46-0	No Data	No Data	Metric Ton/Day	Chengdu Biopurify Phytochemicals Ltd.	Contact Supplier
EC,(-)-Epicatechin Cas No: 490-46-0	USD $ 1.0-1.0 / Gram	100 Gram	10 Gram/Day	Hubei Jusheng Technology Co., Ltd.,	Contact Supplier
High quality L-Epicatechin supplier in China Cas No: 490-46-0	No Data	No Data	No Data	Simagchem Corporation	Contact Supplier
L-Epicatechin Manufacturer/High quality/Best price/In stock Cas No: 490-46-0	USD $ 3.0-3.0 / Kilogram	1 Kilogram	1-100 Metric Ton/Month	Hangzhou Dayangchem Co., Ltd.	Contact Supplier
L-Epicatechin Cas No: 490-46-0	USD $ 1.0-2.0 / Kilogram	1 Kilogram	200 Metric Ton/Month	Crovell Biotech (Hebei) Co., Ltd.	Contact Supplier
L-Epicatechin CAS NO.490-46-0 Cas No: 490-46-0	USD $ 1.0-3.0 / Kilogram	1 Kilogram	10 Kilogram/Day	Hebei yanxi chemical co.,LTD.	Contact Supplier
Factory L-Epicatechin,EC 98% in stock Cas No: 490-46-0	No Data	1 Kilogram	1 Metric Ton/Month	Shaanxi Mingqi Chemical Co., Ltd	Contact Supplier
CAS NO. 490-46-0 L-Epicatechin with best price Cas No: 490-46-0	No Data	100 Gram	20000 Kilogram/Day	Hubei XinRunde Chemical Co., Ltd	Contact Supplier

490-46-0 Usage

Chemical Properties

white to light yellow crystal powde

Uses

Potent antioxidant and antineoplastic agent.

Definition

ChEBI: A catechin with (2R,3R)-configuration.

Uses

Catechin is a polyphenolic flavonoid that has been isolated from a variety of natural sources including tea leaves, grape seeds, and the wood and bark of trees such as acacia and mahogany. Catechin is a more potent antioxidant than ascorbate or α-tocopherol in certain in vitro lipid peroxidation assays. (?)-Epicatechin is a 2R,3R stereoisomer of catechin. Like catechin, (?)-epicatechin is a powerful antioxidant. It inhibits cyclooxygenase 1 (IC50 = 3.2 μM). Also, at 100 μM, (?)-epicatechin induces apoptosis in human adenocarcinoma PC-9 cells and stimulates the inhibition of tumor necrosis factor-α release from BALB-c/3T3 cells treated with epigallocatechin gallate.

490-46-0 Well-known Company Product Price

Brand	(Code)Product description	CAS number	Packaging	Price	Detail
Sigma	(E4018) (−)-Epicatechin ≥98% (HPLC), from green tea	490-46-0	E4018-5MG	1,580.67CNY	Detail
Sigma	(E4018) (−)-Epicatechin ≥98% (HPLC), from green tea	490-46-0	E4018-1MG	455.13CNY	Detail
Sigma	(E1753) (−)-Epicatechin ≥90% (HPLC)	490-46-0	E1753-5G	5,377.32CNY	Detail
Sigma	(E1753) (−)-Epicatechin ≥90% (HPLC)	490-46-0	E1753-1G	1,556.10CNY	Detail
Sigma-Aldrich	(03940590) Epicatechin primary pharmaceutical reference standard	490-46-0	03940590-10MG	3,868.02CNY	Detail
Sigma-Aldrich	(68097) (−)-Epicatechin analytical standard	490-46-0	68097-10MG	3,887.91CNY	Detail

490-46-0SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 17, 2017

Revision Date: Aug 17, 2017

1.Identification

1.1 GHS Product identifier

Product name	(-)-epicatechin

1.2 Other means of identification

Product number	-
Other names	(?)-cis-3,3',4',5,7-Pentahydroxyflavane

1.3 Recommended use of the chemical and restrictions on use

Identified uses	For industry use only.
Uses advised against	no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number	-
Service hours	Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

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