287171-78-2

Upstream product

• 58313-23-8 3-iodobenzoic acid methyl ester 
• 23728-82-7 Tributylstannyl tert-butyl sulfide 
• 75-66-1 2-methylpropan-2-thiol 
• 24398-88-7 ethyl 3-bromobenzoate 

Downstream Products

• 287171-79-3 2-[1-(3-(tert-butylsulfanyl)phenyl)-1-ethoxymethylene]tricyclo[3.3.1.1^3,7]decane 
• 89050-47-5 3,3'-Dithiobis(benzoesaeureethylester) 
• 433711-33-2 2-{ethoxy-[3-(2-nitrophenyldisulfanyl)phenyl]methylene}tricyclo[3.3.1.1^3,7]decane 
• 287171-80-6 2-{ethoxy-[3-(2,4-dinitrophenyldisulfanyl)phenyl]methylene}tricyclo[3.3.1.1^3,7]decane 

Relevant academic research and scientific papers

Site-Selective C?S Bond Formation at C?Br over C?OTf and C?Cl Enabled by an Air-Stable, Easily Recoverable, and Recyclable Palladium(I) Catalyst

This report widens the repertoire of emerging PdI catalysis to carbon–heteroatom, that is, C?S bond formation. While Pd0-catalyzed protocols may suffer from the formation of poisonous sulfide-bound off-cycle intermediates and lack of selectivity, the mechanistically diverse PdI catalysis concept circumvents these challenges and allows for C?S bond formation (S–aryl and S–alkyl) of a wide range of aryl halides. Site-selective thiolations of C?Br sites in the presence of C?Cl and C?OTf were achieved in a general and a priori predictable fashion. Computational, spectroscopic, X-ray, and reactivity data support dinuclear PdI catalysis to be operative. Contrary to air-sensitive Pd0, the active PdI species was easily recovered in the open atmosphere and subjected to multiple rounds of recycling.

Design and synthesis of chemiluminescent probes for the detection of cholinesterase activity

Acetylcholinesterase is one of the most widely used and studied enzymes. Not only does this enzyme regulate neurotransmission (and thus play a key role in neurodegenerative processes) but it is also a prime target for pest control agents and warfare agent

McMurry intermolecular cross-coupling between an ester and a ketone: Scope and limitations

In the course of our studies towards the synthesis of a dioxetane bearing chemiluminescent probe for the detection of thiols, we were faced with the synthesis of sterically hindered benzylic enol ethers. This issue was solved via the use of an intermolecular McMurry cross-coupling between an ester and a ketone. In this article, together with the synthesis of the chemiluminescent probe, the scope and limitations of this low valent titanium based carbon-carbon double bond formation are discussed.