433711-33-2Relevant academic research and scientific papers
McMurry intermolecular cross-coupling between an ester and a ketone: Scope and limitations
Sabelle, Stéphane,Hydrio, Jér?me,Leclerc, Eric,Mioskowski, Charles,Renard, Pierre-Yves
, p. 3645 - 3648 (2002)
In the course of our studies towards the synthesis of a dioxetane bearing chemiluminescent probe for the detection of thiols, we were faced with the synthesis of sterically hindered benzylic enol ethers. This issue was solved via the use of an intermolecular McMurry cross-coupling between an ester and a ketone. In this article, together with the synthesis of the chemiluminescent probe, the scope and limitations of this low valent titanium based carbon-carbon double bond formation are discussed.
Design and synthesis of chemiluminescent probes for the detection of cholinesterase activity
Sabelle, Stephane,Renard, Pierre-Yves,Pecorella, Karine,De Suzzoni-Dezard, Sophie,Creminon, Christophe,Grassi, Jacques,Mioskowski, Charles
, p. 4874 - 4880 (2007/10/03)
Acetylcholinesterase is one of the most widely used and studied enzymes. Not only does this enzyme regulate neurotransmission (and thus play a key role in neurodegenerative processes) but it is also a prime target for pest control agents and warfare agent
