28718-07-2

Upstream product

• 38986-89-9 trans-cinnamoyl fluoride 
• 58521-27-0 potassium 2,3,4,5,6-pentafluorobenzoate 
• 1332714-44-9 3-(2-aminophenylthio)-1-(perfluorophenyl)-3-phenylpropan-1-one 
• 652-29-9 2',3',4',5',6'-pentafluoroacetophenone 
• 100-52-7 benzaldehyde 

Downstream Products

• 54003-54-2 2-(Pentafluorophenyl-phenyl-methyl)-1,3,5-triphenyl-pentane-1,5-dione 
• 1332714-44-9 3-(2-aminophenylthio)-1-(perfluorophenyl)-3-phenylpropan-1-one 
• 1332714-33-6 2-(phenyl)-4-[2,3,5,6-tetrafluoro-4-(2-aminophenylthio)phenyl]-2,3-dihydrobenzo[b][1,4]thiazepine 
• 51973-60-5 1,3-diphenyl-5-(pentafluorophenyl)-4,5-dihydro-1H-pyrazole 
• 1610621-76-5 4-(perfluorophenyl)-2-phenyl-2,3-dihydro-1H-benzo-1,5-diazepine 
• 51973-56-9 3-(pentafluorophenyl)-1,5-diphenyl-4,5-dihydro-1H-pyrazole 
• 54036-73-6 1,3-Bis-pentafluorophenyl-3-phenyl-propan-1-one 

Relevant academic research and scientific papers

Decarboxylative Cross-Coupling of Acyl Fluorides with Potassium Perfluorobenzoates

We report the transition metal-free decarboxylative cross-coupling reactions of acyl fluorides with potassium perfluorobenzoates. Compared with traditional transition metal-catalyzed cross-couplings, this protocol presents an extremely environmentally ben

Reactions of polyfluorinated chalcones with o-aminobenzenethiol and its zinc salt

The reactions of polyfluorochalcones with o-aminothiophenol in methanol in the presence of HCl afford polyfluorine-substituted 2,3-dihydrobenzo[b][1,5] thiazepines. In some cases, the cyclization is accompanied by fluorine substitution in the perfluorophenyl ring. Probably, the formation of thiazepines proceeds through the Michael thia-adduct. The Zn salt of o-aminothiophenol reacts with chalcones in DMF exclusively via fluorine substitution.

Graphite oxide as an auto-tandem oxidation-hydration-aldol coupling catalyst

Graphite oxide (GO) was found to function as an auto-tandem oxidation-hydration-aldol coupling catalyst for the formation of chalcones in a single reaction vessel. Various alkynes or alcohols were hydrated or oxidized in situ to their corresponding methyl ketones or aldehydes, respectively, which underwent a subsequent Claisen-Schmidt condensation. Each of the aforementioned reactions proceeded in the absence of metals (confirmed by inductively coupled plasma mass spectrometry, ICP-MS) and afforded a range of chalcone products in good to excellent yields from commercially available starting materials.