287194-47-2

Upstream product

• 617-86-7 triethylsilane 
• 6228-98-4 phenylthioacetylene 
• 287194-57-4 [2-(2-benzyloxy-6-methyldodecahydro-4,8,12-trioxadibenzo[a,d]cycloocten-3-yl)-1-phenylsulfanylvinyl]triethyl silane 
• 287194-56-3 2-benzyloxy-6-methyl-3-phenylsulfanylethynyldodecahydro-4,8,12-trioxadibenzo[a,d]cyclooctene-3-ol 
• 287194-46-1 2-benzyloxy-6-methyl-3-phenylsulfanylethynyldodecahydro-4,8,12-trioxadibenzo[a,d]cyclooctene 
• 272787-70-9 6-[2-benzyloxy-3-(tert-butyldiphenylsilyloxy)propyl]-9-methyldecahydro-1,5-dioxabenzocyclooctene-7,8-diol 
• 272787-71-0 [2-benzyloxy-3-(2,2,11-trimethyldecahydro-1,3,5,9-tetraoxabenzo[a]cyclopenta[e]cycloocten-4-yl)propoxy]-tert-butyldiphenyl silane 
• 272787-62-9 imidazole-1-carbothioic acid O-(2-benzyloxy-6-methyl-3-oxo-dodecahydro-4,8,12-trioxadibenzo[a,d]cycloocten-5-yl) ester 
• 272787-72-1 (S)-2-Benzyloxy-3-((3aR,4R,5aS,9aR,11S,11aS)-2,2,11-trimethyl-decahydro-1,3,5,9-tetraoxa-benzo[a]cyclopenta[e]cycloocten-4-yl)-propan-1-ol 
• 272787-60-7 2-benzyloxy-3-(2,2,11-trimethyldecahydro-1,3,5,9-tetraoxabenzo[a]cyclopenta[e]cycloocten-4-yl)propionaldehyde 
• 272787-61-8 2-benzyloxy-5-hydroxy-6-methyldodecahydro-4,8,12-trioxadibenzo[a,d]cyclooctene-3-one 
• 272787-73-2 2-benzyloxy-6-methyldodecahydro-4,8,12-trioxadibenzo[a,d]cyclooctene-3,5-diol 
• 272787-63-0 2-benzyloxy-6-methyldodecahydro-4,8,12-trioxadibenzo[a,d]cyclooctene-3-one 
• 287194-58-5 [(Z)-1-Benzenesulfonyl-2-((2S,3R,4aS,6S,7aR,11aS,12aR)-2-benzyloxy-6-methyl-dodecahydro-4,8,12-trioxa-dibenzo[a,d]cycloocten-3-yl)-vinyl]-triethyl-silane 

Downstream Products

• 300343-66-2 3-[1-benzenesulfonylmethyl-6-benzyloxy-7-(tert-butyldiphenylsilyloxy)-4-methoxyhept-2-ynyl]-6-methyldodecahydro-4,8,12-trioxadibenzo[a,d]cycloocten-2-ol 

Relevant academic research and scientific papers

Heteroconjugate addition strategy for the synthesis of the (HIJ)K-ring fragment of ciguatoxin

An efficient strategy for the synthesis of the (HIJ)K-ring system of ciguatoxin has been established based on a combination strategy of a heteroconjugate addition reaction and a cobalt complex-mediated cyclization.

Synthetic studies on the HIJK-ring fragment of ciguatoxin

Synthesis of the tetracyclic HIJK-ring fragment of ciguatoxin with high stereoselectivity has been achieved starting from a sugar derivative directed toward the synthesis of the right part of ciguatoxin. Sonogashira coupling of a vinyl iodide with an acetylene derivative, cobalt complex-mediated (seven- and eight-membered ring) cyclizations and a heteroconjugate addition reaction play important roles in the current research work. (C) 2000 Elsevier Science Ltd.