287379-32-2

Basic information

• Product Name: 4-But-2-ynyloxy-N-methyl-benzenesulfonamide
• Synonyms: 4-But-2-ynyloxy-N-methyl-benzenesulfonamide
• CAS NO: 287379-32-2
• Molecular Weight: 239.295
• Mol File: 287379-32-2.mol
• Article Data: 5

Chemical Properties

• CAS DataBase Reference: 4-But-2-ynyloxy-N-methyl-benzenesulfonamide(CAS DataBase Reference)
• NIST Chemistry Reference: 4-But-2-ynyloxy-N-methyl-benzenesulfonamide(287379-32-2)
• EPA Substance Registry System: 4-But-2-ynyloxy-N-methyl-benzenesulfonamide(287379-32-2)

Safety Data

• Hazardous Substances Data: 287379-32-2(Hazardous Substances Data)

Upstream product

• 286459-94-7 4-but-2-ynyloxybenzenesulfonyl chloride 
• 74-89-5 methylamine 

Downstream Products

• 287379-39-9 4-[(4-But-2-ynyloxy-benzenesulfonyl)-methyl-amino]-3-methyl-isothiazolo[5,4-b]pyridine-5-carboxylic acid ethyl ester 
• 287407-69-6 methyl 2-[{[4-(2-butynyloxy)phenyl]sulfonyl}(methyl)amino]-2-phenylacetate 
• 287379-33-3 4-[(4-but-2-ynyloxy-benzenesulfonyl)-methyl-amino]-1,3-dimethyl-1H-pyrazolo[3,4-b]pyridine-5-carboxylic acid ethyl ester 
• 287379-47-9 ethyl 8-bromo-4-[{[4-(2-butynyloxy)phenyl]sulfonyl}(methyl)amino]-3-quinolinecarboxylate 
• 287379-35-5 4-[(4-but-2-ynyloxy-benzenesulfonyl)-methyl-amino]-3-methyl-isoxazolo[5,4-b]pyridine-5-carboxylic acid ethyl ester 
• 287379-37-7 4-[(4-But-2-ynyloxy-benzenesulfonyl)-methyl-amino]-8-methoxy-quinoline-3-carboxylic acid ethyl ester 

Relevant articles and documents

ACETYLENIC ALPHA-AMINO ACID-BASED SULFONAMIDE HYDROXAMIC ACID TACE INHIBITORS

Compound of the formula (B) are useful in treating disease conditions mediated by TNF- alpha , such as rheumatoid arthritis, osteoarthritis, sepsis, AIDS, ulcerative colitis, multiple sclerosis, Crohn's disease and degenerative cartilage loss.

Acetylenic ortho-sulfonamido and phosphinic acid amido bicyclic heteroaryl hydroxamic acids as TACE inhibitors

are provided wherein P and Q are or provided that when P is , Q is , and vice versa; which are useful in disease conditions mediated by TNF-α, such as rheumatoid arthritis, osteoarthritis, sepsis, AIDS, ulcerative colitis, multiple sclerosis, Crohn's disease and degenerative cartilage loss.

Acetylenic α-amino acid-based sulfonamide hydroxamic acid tace inhibitors

Compounds of the formula: are useful in treating disease conditions mediated by TNF-α, such as rheumatoid arthritis, osteoarthritis, sepsis, AIDS, ulcerative colitis, multiple sclerosis, Crohn's disease and degenerative cartilage loss.