287401-28-9

Basic information

• Product Name: benzyl 1,1-dimethyl-3-oxo-2-oxa-5-azaspiro[3.4]octane-5-carboxylate
• Synonyms: ZNSFQVSZRRZLOI-UHFFFAOYSA-N;2-Oxa-5-azaspiro[3.4]octane-5-carboxylic acid, 1,1-diMethyl-3-oxo-, phenylMethyl ester
• CAS NO: 287401-28-9
• Molecular Formula: C₁₆H₁₉NO₄
• Molecular Weight: 289.33
• Mol File: 287401-28-9.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 436.9°C at 760 mmHg
• Flash Point: 218°C
• Density: 1.25g/cm³
• Vapor Pressure: 7.8E-08mmHg at 25°C
• Refractive Index: 1.579
• CAS DataBase Reference: benzyl 1,1-dimethyl-3-oxo-2-oxa-5-azaspiro[3.4]octane-5-carboxylate(CAS DataBase Reference)
• NIST Chemistry Reference: benzyl 1,1-dimethyl-3-oxo-2-oxa-5-azaspiro[3.4]octane-5-carboxylate(287401-28-9)
• EPA Substance Registry System: benzyl 1,1-dimethyl-3-oxo-2-oxa-5-azaspiro[3.4]octane-5-carboxylate(287401-28-9)

Safety Data

• Hazardous Substances Data: 287401-28-9(Hazardous Substances Data)

Upstream product

• 67-64-1 acetone 
• 17543-45-2 Z-Pro-OPfp 

Relevant articles and documents

The first syntheses of the 1-oxo-2-oxa-5-azaspiro[3.4]octane ring system found in oxazolomycin

matrix presented L-Proline was utilized to prepare an optically active 1-oxo-2-oxa-5-azaspiro[3.4]octane for the first time. The synthesis of the racemic system, using a tandem aldol-lactonization reaction, is also described. Ruthenium tetroxide oxidation of these compounds afforded the corresponding spiro β-lactone γ-lactams.