2875-10-7 Usage
Uses
Used in Pharmaceutical Industry:
2,3,5,6-Tetrafluoropyridine-4-carboxylic acid is used as a key intermediate in the synthesis of various pharmaceutical drugs. Its strong electron-withdrawing properties make it a valuable component in the development of novel drug candidates with improved pharmacological properties and therapeutic efficacy.
Used in Agrochemical Industry:
In the agrochemical industry, 2,3,5,6-tetrafluoropyridine-4-carboxylic acid is used for the synthesis of agricultural products, such as pesticides and herbicides. Its unique chemical properties contribute to the development of more effective and targeted agrochemicals for crop protection and management.
Used as a Building Block for Fluorinated Compounds:
2,3,5,6-Tetrafluoropyridine-4-carboxylic acid serves as a versatile building block for the preparation of other fluorinated compounds. Its presence in these compounds can enhance their chemical and biological properties, making them suitable for various applications in different industries, including pharmaceuticals, materials science, and agrochemicals.
Check Digit Verification of cas no
The CAS Registry Mumber 2875-10-7 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 2,8,7 and 5 respectively; the second part has 2 digits, 1 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 2875-10:
(6*2)+(5*8)+(4*7)+(3*5)+(2*1)+(1*0)=97
97 % 10 = 7
So 2875-10-7 is a valid CAS Registry Number.
InChI:InChI=1/C6HF4NO2/c7-2-1(6(12)13)3(8)5(10)11-4(2)9/h(H,12,13)
2875-10-7Relevant articles and documents
Synthesis of some fluorine-containing pyridinealdoximes of potential use for the treatment of organophosphorus nerve-agent poisoning
Timperley, Christopher M.,Banks, R. Eric,Young, Ian M.,Haszeldine, Robert N.
scheme or table, p. 541 - 547 (2011/09/15)
Fluoroheterocyclic aldoximes were screened as therapeutic agents for the treatment of anticholinesterase poisoning. 2-Fluoropyridine-3- and -6-aldoxime, and 3-fluoropyridine-2- and -4-aldoxime, were synthesised. Attempts to obtain 3,5,6-trifluoropyridine-2,4-bis(aldoxime) and -2-aldoxime, however, proved unsuccessful. Pentafluorobenzaldoxime was prepared by oximation of pentafluorobenzaldehyde. Acid dissociation constants (pKa) and second-order rate constants (kox-) of the fluorinated pyridinealdoximes towards sarin were measured. 2,3,5,6-Tetrafluoropyridine-4- aldoxime had the best profile: its kox- approached that of the therapeutic oxime P2S (310 vs. 120 l mol-1 min-1), but its higher pKa (9.1 vs. 7.8) fell short of the target figure of 8 required for reactivation of inhibited acetylcholinesterase in vivo. N-alkylation of the fluorinated pyridine-aldoximes may reduce their pK a nearer to 8 and enhance their therapeutic potential. Crown Copyright
