2876-44-0Relevant articles and documents
Nickel-Catalyzed Csp2-Csp3 Cross-Coupling via C-O Bond Activation
Guo, Lin,Hsiao, Chien-Chi,Yue, Huifeng,Liu, Xiangqian,Rueping, Magnus
, p. 4438 - 4442 (2016)
A new and efficient nickel-catalyzed alkylation of CAr-O electrophiles with B-alkyl-9-BBNs is described. The transformation is characterized by its functional group tolerance and provides a practical and versatile access to various Csp2/s
C-F activation for C(sp2)-C(sp3) cross-coupling by a secondary phosphine oxide (SPO)-nickel complex
Müller, Valentin,Ghorai, Debasish,Capdevila, Lorena,Messinis, Antonis M.,Ribas, Xavi,Ackermann, Lutz
supporting information, p. 7034 - 7040 (2020/09/15)
A secondary phosphine oxide (SPO)-nickel catalyst allowed the activation of otherwise inert C-F bonds of unactivated arenes in terms of challenging couplings with primary and secondary alkyl Grignard reagents. The C-F activation is characterized by mild reaction conditions and high levels of branched selectivity. Electron-rich and electron-deficient arenes were suitable electrophiles for this transformation. In addition, this strategy also proved suitable to heterocycles and for the activation of C-O bonds under slightly modified conditions.
Nickel-Catalyzed Reductive Cross-Coupling of Aryl Triflates and Nonaflates with Alkyl Iodides
Sumida, Yuto,Sumida, Tomoe,Hosoya, Takamitsu
, p. 3590 - 3601 (2017/08/16)
A nickel-catalyzed cross-electrophile coupling of aryl triflates and nonaflates with alkyl iodides using manganese(0) as a reductant is described. The method is applicable to the reductive alkylation of various aryl sulfonates, including o -borylaryl triflate, which enabled efficient construction of diverse alkylated arenes under mild conditions.