2877-13-6

Basic information

• Product Name: AcetaMide, 2,2,2-trichloro-N-(4-chlorophenyl)-
• Synonyms: AcetaMide, 2,2,2-trichloro-N-(4-chlorophenyl)-
• CAS NO: 2877-13-6
• Molecular Formula: C₈H₅Cl₄NO
• Molecular Weight: 272.9434
• Mol File: 2877-13-6.mol
• Article Data: 2

Chemical Properties

• Boiling Point: 356.9°Cat760mmHg
• Flash Point: 169.6°C
• Appearance: /
• Density: 1.618g/cm³
• Vapor Pressure: 2.83E-05mmHg at 25°C
• Refractive Index: 1.628
• CAS DataBase Reference: AcetaMide, 2,2,2-trichloro-N-(4-chlorophenyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: AcetaMide, 2,2,2-trichloro-N-(4-chlorophenyl)-(2877-13-6)
• EPA Substance Registry System: AcetaMide, 2,2,2-trichloro-N-(4-chlorophenyl)-(2877-13-6)

Safety Data

• Hazardous Substances Data: 2877-13-6(Hazardous Substances Data)

Usage

InChI:InChI=1/C8H5Cl4NO/c9-5-1-3-6(4-2-5)13-7(14)8(10,11)12/h1-4H,(H,13,14)

Upstream product

• 106-47-8 4-chloro-aniline 
• 76-02-8 trifluoroacetyl chloride 
• 76-03-9 trichloroacetic acid 
• 116-16-5 1,1,1,3,3,3-hexachloro-propan-2-one 

Downstream Products

• 449176-04-9 1-(4-chlorophenyl)-3-(6-nitrobenzo[d]thiazol-2-yl)urea 
• 56311-82-1 1-(6-chlorobenzo[d]thiazol-2-yl)-3-(4-chlorophenyl)urea 
• 91025-96-6 N-(4-chlorophenyl)-N'-(6-methylbenzothiazol-2-yl)urea 
• 52625-27-1 N-(4-chlorophenyl)morpholine-4-carboxamide 
• 940-36-3 (4-chloro-phenyl)-carbamic acid methyl ester 
• 41374-66-7 methyl 2-[(4-chlorophenyl)amino]-2-oxoacetate 
• 106-47-8 4-chloro-aniline 

Relevant articles and documents

A novel synthesis of isocyanates and ureas via β-elimination of haloform

A novel synthesis of isocyanates via base-induced β-elimination of haloform from N-monosubstituted trihaloacetamides is described. The rate of reaction exhibits a strong dependence on the nature of the trihalomethyl group. Thus, while the reaction of tribromoacetamides proceeds at room temperature and the reaction of trichloroacetamides requires heating in polar solvents, no reaction could be observed for any of the corresponding trifluoro derivatives. This novel β-elimination of haloform from stable and readily available trihaloacetamides was applied to a 'one-pot' synthesis of ureas which avoids the use of phosgene and isolation of isocyanates.