91025-96-6Relevant academic research and scientific papers
Microwave promoted environmentally benign synthesis of 2- aminobenzothiazoles and their urea derivatives
Li, Zheng,Xiao, Shuxiu,Tian, Guoqiang,Zhu, Anguo,Feng, Xu,Liu, Jing
experimental part, p. 1124 - 1133 (2009/04/06)
2-Aminobenzothiazoles were efficiently synthesized using stable, crystalline tetrabutylammonium tribromide instead of toxic, corrosive liquid bromine under solvent-free and microwave irradiation condition. Furthermore, benzothiazol-2-ylureas were synthesized in good to high yield by reactions of 2-aminobenzothiazoles with N-trichloroacetanilides, which were used as a substitute for toxic, unstable isocyanates, under microwave irradiation condition. This protocol has advantages of no utilization of hazardous chemicals, rapid reaction rate, high yield, and easy work-up procedure. Copyright Taylor & Francis Group, LLC.
