287730-08-9

Upstream product

• 443797-18-0 tert-butyl 2-(2-(methoxy(methyl)amino)-2-oxoethyl)pyrrolidine-1-carboxylate 
• 194154-91-1 (+/-)-1-(tert-Butoxycarbonyl)pyrrolidine-2-acetic acid 
• 211310-10-0 2-(methoxy-N-methylcarbamoyl)piperidine-1-carboxylic acid tert-butyl ester 
• 98303-20-9 1-(tert-butoxycarbonyl)piperidine-2-carboxylic acid 
• 443797-19-1 (+/-)-1-(t-butoxycarbonyl)-2-(2-oxo-3-butenyl)pyrrolidine 
• 106-45-6 para-thiocresol 

Downstream Products

• 2407-99-0 hexahydroindolizin-7(1H)-one 

Relevant academic research and scientific papers

BICYCLIC UNSATURATED TERTIARY AMINE COMPOUND

The present invention provides a bicyclic unsaturated tertiary amine compound capable of inhibiting the production of inflammatory cytokines.A compound of the following formula (1): (wherein, A represents pyrrole or pyrazole, R1 represents an aryl group or a heteroaryl group which may be substituted, R2 represents a heteroaryl group which may be substituted, and R3 represents an indolizine group), or a pharmacologically acceptable salt thereof, a pharmacologically acceptable ester thereof or other pharmacologically acceptable derivative thereof.

COMPOUNDS SUBSTITUTED WITH BICYCLIC AMINO GROUPS

[Object]The object of the present invention is to provide compounds which are able to inhibit the production of inflammatory cytokines.[Solution]Compounds of the general formula (I) below, or pharmacologically acceptable salts, esters or other derivatives