28792-98-5Relevant articles and documents
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Buess,Jones
, p. 5558 (1954)
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Visible-Light-Promoted Radical Cyclization of N -Arylvinylsulfonamides: Synthesis of CF 3/CHF 2/CH 2CF 3-Containing 1,3-Dihydrobenzo[ c ]isothiazole 2,2-Dioxide Derivatives
Vytla, Devaiah,Kaliyaperumal, Kumargurubaran,Velayuthaperumal, Rajeswari,Shaw, Parinita,Gautam, Raj,Mathur, Arvind,Roy, Amrita
supporting information, p. 667 - 682 (2021/11/13)
A photocatalyzed and highly efficient trifluoromethylation of N-arylvinylsulfonamides using commercially available CF3SO2Cl as the trifluoromethyl radical source under blue LEDs is reported. The reaction proceeds through radical cyclization under mild con
Diastereoselective Monofluorocyclopropanation Using Fluoromethylsulfonium Salts
Melngaile, Renate,Sperga, Arturs,Baldridge, Kim K.,Veliks, Janis
supporting information, p. 7174 - 7178 (2019/09/12)
Diarylfluoromethylsulfonium salts, alternatives to freons or advanced fluorinated building blocks, are bench stable and easy-to-use sources of direct fluoromethylene (:CHF) transfer to alkenes. These salts enabled development of a trans-selective monofluorinated Johnson-Corey-Chaykovsky reaction with vinyl sulfones or vinyl sulfonamides to access synthetically challenging monofluorocyclopropane scaffolds. The described method offers rapid access to monofluorinated cyclopropane building blocks with further functionalization opportunities to deliver more complex synthetic targets diastereoselectively.