287961-30-2Relevant academic research and scientific papers
Mannich reactions catalyzed by perchloric acid in Triton X10 aqueous micelles
Lu, Guo-ping,Cai, Chun
, p. 745 - 748 (2010)
Perchloric acid can efficiently catalyze the one-pot, three-component Mannich reactions of ketones with aromatic aldehydes and aromatic amines in Triton X10 aqueous micelles at room temperature. This protocol has several advantages such as excellent yields, mild conditions, clear reaction profile and simple work-up procedure.
Bismuth(III) chloride-catalyzed one-pot Mannich reaction: three-component synthesis of β-amino carbonyl compounds
Li, Hua,Zeng, Hong-yao,Shao, Hua-wu
scheme or table, p. 6858 - 6860 (2010/05/03)
A simple and efficient method has been developed for the one-pot Mannich reaction of β-amino carbonyl compounds from aromatic aldehydes, aromatic ketones and aromatic amines in the presence of a catalytic amount of bismuth trichloride.
