287968-64-3Relevant academic research and scientific papers
Synthesis and characterization of Bis-quinazolines from linear tetra-amines involving 2-(aminomethyl)benzenamine with aldehydes
Azadbakht, Reza,Khodabandeh, Maryame,Keypour, Hassan,Baghdad Abadi, Reza Haji Hosseini,Rudbari, Hadi Amiri
, p. 979 - 981 (2013)
Three tetra-amine compounds 2-((2-(2-aminobenzylamino)ethylamino)methyl) benzenamine (L1), 2-((3-(2-aminobenzylamino)propylamino)methyl) benzenamine (L2), and 2-((4-(2-aminobenzylamino)butylamino)methyl) benzenamine (L3) were synthesized and then their reaction with 2-hydroxybenzaldehyde, 2-nitrobenzaldehyde, and 2-hydroxy-3-methoxybenzaldehyde were investigated. Treatment of L1, L2, and L3 with the former aldehydes gave derivatives of quinazolines in a good yield. The products have been studied with IR, 1H NMR, 13C NMR, COSY, HMQC, and microanalysis.
Induction of apoptosis by aryl-substituted diamines: Role of aromatic group substituents and distance between nitrogens
Burns, Mark R,LaTurner, Solveig,Ziemer, Josh,McVean, Maralee,Devens, Bruce,Carlson,Graminski, Gerard F.,Vanderwerf, Scott M.,Weeks, Reitha S.,Carreon, Jay
, p. 1263 - 1267 (2007/10/03)
A series of aromatic substituted diamines was synthesized and characterized for their cytotoxic profiles against human breast and prostate tumor cell lines. Following a structure function analysis of the effects of changes of the benzyl substituents and t
