288089-74-7Relevant academic research and scientific papers
Ni-Catalyzed Carboxylation of Unactivated Alkyl Chlorides with CO2
B?rjesson, Marino,Moragas, Toni,Martin, Ruben
supporting information, p. 7504 - 7507 (2016/07/06)
A catalytic carboxylation of unactivated primary, secondary, and tertiary alkyl chlorides with CO2 at atmospheric pressure is described. This protocol represents the first intermolecular cross-electrophile coupling of unactivated alkyl chlorides, thus leading to new knowledge in the cross-coupling arena.
Nickel-Catalyzed Reductive Amidation of Unactivated Alkyl Bromides
Serrano, Eloisa,Martin, Ruben
supporting information, p. 11207 - 11211 (2016/10/13)
A user-friendly, nickel-catalyzed reductive amidation of unactivated primary, secondary, and tertiary alkyl bromides with isocyanates is described. This catalytic strategy offers an efficient synthesis of a wide range of aliphatic amides under mild conditions and with an excellent chemoselectivity profile while avoiding the use of stoichiometric and sensitive organometallic reagents.
Stereochemical course of the hydrogen migration in the boron trifluoride etherate-catalyzed rearrangement of 1,1-disubstituted epoxides
Hara, Noriyuki,Mochizuki, Akiyoshi,Tatara, Akinori,Fujimoto, Yoshinori
, p. 1859 - 1868 (2007/10/03)
Mechanistic studies on the BF3.Et2O-catalyzed rearrangement of optically active, regioselectively deuterated 1,1-disubstituted epoxides to aldehydic products revealed that the two hydrogens migrate at the migration terminus with oppo
