288099-33-2

Upstream product

• 1004-66-6 2-methoxy-1,3-dimethylbenzene 
• 52239-62-0 methyl 2-methoxy-3-methylbenzoate 
• 83-40-9 3-methylsalicylic acid 
• 1427363-87-8 methyl 3-(hydroxymethyl)-2-methoxybenzoate 
• 186312-96-9 methyl 2-methoxy-3-formylbenzoate 
• 1951-38-8 2-methoxyisophthalic acid 
• 36727-13-6 2-methoxy-1,3-benzenedicarboxylic acid dimethyl ester 

Downstream Products

• 787629-29-2 2-methoxy-3-[N'-(2-octyloxy-benzoyl)-hydrazinocarbonyl]-benzoic acid methyl ester 
• 1052717-02-8 C₄₈H₆₆N₄O₁₂ 
• 1031691-49-2 C₆₂H₁₀₁N₇O₁₂ 
• 787629-26-9 N,N'-di-((2-methoxy-3-hydrazinocarbonylbenzoyl)amino) 4,5-dioctyloxy-iso-phthalamide 
• 787629-22-5 N,N'-di-((2-methoxy-3-methoxycarbonylbenzoyl)amino) 4,6-dioctyloxy-iso-phthalamide 
• 787629-27-0 N,N'-di-(3-hydroxycarbonyl-2-methoxy)benzoyl 4,6-dioctyloxy-iso-phthalohydrazide 
• 939374-76-2 C₃₀H₄₂N₄O₁₂ 
• 939374-74-0 C₄₀H₅₀N₄O₁₆ 
• 107020-28-0 2-methoxy-3-methoxycarbonylbenzoyl chloride 
• 787629-32-7 2-methoxy-3-{N'-[5-(N'-{2-methoxy-3-[N'-(2-octyloxy-benzoyl)-hydrazinocarbonyl]-benzoyl}-hydrazinocarbonyl)-2,4-bis-octyloxy-benzoyl]-hydrazinocarbonyl}-benzoic acid methyl ester 

Relevant academic research and scientific papers

Complexes and Ligands

The present application provides ligands and fluorescent or luminescent complexes comprising these ligands.

ARYL AND HETEROARYL-CARBOXAMIDE SUBSTITUTED HETEROARYL COMPOUNDS AS TYK2 INHIBITORS

Novel carboxamide substituted compounds of Formula (I) are disclosed; as well as processes for their preparation, pharmaceutical compositions comprising them and their use in therapy as inhibitors of Tyrosine Kinase 2 (Tyk2).

Siderophore inspired tetra- and octadentate antenna ligands for luminescent Eu(III) and Tb(III) complexes

Following the success of the siderophore-inspired 1,2-hydroxypyridonate (HOPO) and 2-hydroxisophthalamide (IAM) chromophores in Eu(III) and Tb(III) luminescence, we designed three new ligands bearing both chromophores. Syntheses of the octadentate ligands

Benzylic hydroxylation of aromatic compounds by P450 BM3

Cytochrome P450 BM3 monooxygenase from Bacillus megaterium and its variants are promising catalysts for organic synthesis. Aiming at the identification of variants for selective hydroxylation of functionalised aromatic compounds, the double mutant F87A L188C showed remarkably improved catalytic activity towards a set of tested toluene derivatives. The apparent catalytic efficiency of this variant towards the model substrate methyl 2-methoxy-3-methylbenzoate was 63.6 s-1 M-1, which is 535-fold higher compared to that of wild-type BM3. Furthermore, the double mutant selectively catalysed the benzylic hydroxylation of numerous toluene derivatives, especially in the presence of carbonyl- or carboxyl-functions that are directly attached to the aromatic ring. Preparative scale conversion resulted in efficient production of methyl 3-(hydroxymethyl)-2-methoxybenzoate (73% yield) which proved that F87A L188C is a suitable, efficient and sustainable catalyst for the introduction of benzylic hydroxyl groups in general.

Hydrogen-bonding-induced planar, rigid, and zigzag oligoanthranilamides. Synthesis, characterization, and self-assembly of a metallocyclophane

Four oligoanthranilamides 1-4, which are incorporated with three, five, seven, or nine benzene units, respectively, have been synthesized and characterized. X-ray analysis, 1D and 2D 1H NMR, and IR experiments reveal that all the new oligoamide