36727-13-6

Upstream product

• 1951-38-8 2-methoxyisophthalic acid 
• 1004-66-6 2-methoxy-1,3-dimethylbenzene 
• 74-88-4 methyl iodide 
• 67-56-1 methanol 
• 420-37-1 trimethoxonium tetrafluoroborate 
• 922-69-0 1,1-dimethoxyethylene 
• 922-67-8 propynoic acid methyl ester 
• 193544-53-5 methyl (R)-(-)-5-tert-butyldimethylsiloxyhex-2-ynoate 
• 606-19-9 2-hydroxyisophthalic acid 

Downstream Products

• 36669-06-4 dimethyl 2-hydroxyisophthalate 
• 288099-33-2 2-methoxyisophthalic acid monomethyl ester 
• 1951-37-7 1-methoxybenzene-2,6-dicarboxaldehyde 
• 111635-74-6 2-methoxy-1,3-benzenedimethanol 
• 1198616-74-8 methoxyisophthalohydrazide 
• 107020-25-7 2,3,4,9-tetrahydro-2-(2-methoxy-3-methoxycarbonylbenzoyl)-1-methylene-1H-pyrido<3,4-b>indole 
• 96400-54-3 naucleficine 
• 107020-28-0 2-methoxy-3-methoxycarbonylbenzoyl chloride 
• 924637-95-6 2-hydroxy-1,3-bis-(3-oxo-3-(2-hydroxyphenyl)-propionyl)-benzene 
• 107020-24-6 Potassium; 2-methoxy-3-methoxycarbonyl-benzoate 

Relevant academic research and scientific papers

Complexes and Ligands

The present application provides ligands and fluorescent or luminescent complexes comprising these ligands.

ARYL AND HETEROARYL-CARBOXAMIDE SUBSTITUTED HETEROARYL COMPOUNDS AS TYK2 INHIBITORS

Novel carboxamide substituted compounds of Formula (I) are disclosed; as well as processes for their preparation, pharmaceutical compositions comprising them and their use in therapy as inhibitors of Tyrosine Kinase 2 (Tyk2).

Siderophore inspired tetra- and octadentate antenna ligands for luminescent Eu(III) and Tb(III) complexes

Following the success of the siderophore-inspired 1,2-hydroxypyridonate (HOPO) and 2-hydroxisophthalamide (IAM) chromophores in Eu(III) and Tb(III) luminescence, we designed three new ligands bearing both chromophores. Syntheses of the octadentate ligands

Externally and Internally Functionalized Copper(II) β-Diketonate Molecular Squares

Five functionalized bis(β-diketones) and their Cu(II) molecular squares are described. The new bis(β-diketones), m-pbhxH2 (3), 5-MeO-m-pbaH2 (4), 5-BuO-m-pbaH2 (5), 2-MeO-m-pbaH2 (6), and 2-MeO-m-pbprH2/su

Syntheses of four new pyridinium phenolates with caged phenolate functionalities as chromophores for quadratic optics

Semi-empirical calculations as well as our preliminary studies indicate an increase of the nonlinear response of pyridinium phenolates with the raise of their interplanar angle. Unfortunately, the tendency of previously synthesized zwitterionic compounds

Multinuclear non-heme iron complexes for double-strand DNA cleavage

The cytotoxicity of the antitumor drug BLM is believed to be related to the ability of the corresponding iron complex (Fe-BLM) to engage in oxidative double-strand DNA cleavage. The iron complex of the ligand N4Py (Fe-N4Py; N4Py = N,N-bis(2-pyridyl)-N-bis

Pigments of fungi. LXIX.* Total synthesis of (R)-ochratoxin α and the formal total synthesis of ochratoxin A

(R)-Ochratoxin α, the monochiral carboxylic acid component of the biologically active dipeptide ochratoxin A, is synthesized for the first time over nine steps from (R)-propylene oxide. The method constitutes a versatile and general route to functionalized dihydroisocoumarins.

Salicylamide-lanthanide complexes for use as luminescent markers

The present invention provides luminescent lanthanide metal chelates comprising a metal ion of the lanthanide series and a complexing agent comprising at least one salicylamidyl moiety. Also provided are probes incorporating the salicylamidyl ligands of t

Protected nucleoside and method for its synthesis

The present invention relates to a nucleoside having the formula: STR1 where R1 is a hydrogen or a protecting group; R2 is a hydrogen or a coupling group; R3 and R4 are each either a hydrogen or an alkyl group, where R3 and R4 can be connected in a ring; R5 is a hydrogen, an alkyl group, or a carboxylic ester group; R6 is a hydrogen, an alkyl group, or a carboxylic ester group; R7 is a hydrogen, a nitro group, a halogen, a cyano group, or an alkyl group, where R7 is attached at either position 4, 5 or 6; and Base is a protected heterocyclic base. Further, the present invention relates to a method of making the nucleoside and a method of oligomer synthesis utilizing the nucleoside.

Photocyclization of enamides. XXXIV. A practical total synthesis of aromatic yohimboid alkaloids, oxogambirtannine and naucleficine

Total synthesis of naucleficine (3a) was accomplished for the first time via an alkaloid, oxogambirtannine (3b), which was efficiently prepared by photocyclization of the o-methoxy-enamide 2b. The method is a practical one, suitable for large-scale preparation.