288100-99-2Relevant academic research and scientific papers
Preparation of disubstituted phenyl propargyl alcohols, their use in oxathiolene oxide synthesis, and evaluation of the oxathiolene oxide products as anticarcinogenic enzyme inducers
Ying, Maben,Smentek, Matthew G.,Ma, Rong,Day, Cynthia S.,Torti, Suzy V.,Welker, Mark E.
experimental part, p. 242 - 251 (2010/04/23)
A number of alkynols have been prepared by Sonogoshira coupling of propargyl alcohol to disubstituted aromatic halides. Chelation controlled addition of organometallic nucleophiles to these alkynols was then affected followed by the addition of sulfur dio
5,5-Diaryl-2-amino-4-pentenoates as novel, potent, and selective glycine transporter type-2 reuptake inhibitors
Isaac, Methvin,Slassi, Abdelmalik,Silva, Kathleen Da,Arora, Jalaj,MacLean, Neil,Hung, Bill,McCallum, Kirk
, p. 1371 - 1373 (2007/10/03)
A novel series of 5,5-diaryl-2-amino-4-pentenoates was synthesized and found to be potent and selective glycine transporter type-2 reuptake inhibitors.
Synthesis of chiral and geometrically defined 5,5-diaryl-2-amino-4-pentenoates: Novel amino acid derivatives
Isaac, Methvin,Slassi, Abdelmalik,Da Silva, Kathleen,Xin, Tao
, p. 2957 - 2960 (2007/10/03)
A novel series of 5,5-diaryl-2-amino-4-pentenoates were synthesized. Chirally defined substrates were obtained efficiently using Oppolzer's sultam as a chiral auxiliary and a palladium-catalyzed stereoselective hydrostannylation.
