288161-82-0

Basic information

• Product Name: N-(1-butyl-1-hydroxymethyl-pentyl)-4-fluoro-benzenesulfonamide
• CAS NO: 288161-82-0
• Molecular Weight: 331.452
• Mol File: 288161-82-0.mol

Chemical Properties

• CAS DataBase Reference: N-(1-butyl-1-hydroxymethyl-pentyl)-4-fluoro-benzenesulfonamide(CAS DataBase Reference)
• NIST Chemistry Reference: N-(1-butyl-1-hydroxymethyl-pentyl)-4-fluoro-benzenesulfonamide(288161-82-0)
• EPA Substance Registry System: N-(1-butyl-1-hydroxymethyl-pentyl)-4-fluoro-benzenesulfonamide(288161-82-0)

Safety Data

• Hazardous Substances Data: 288161-82-0(Hazardous Substances Data)

Upstream product

• 349-88-2 4-Fluorobenzenesulfonyl chloride 
• 288161-81-9 di-n-butyl-ethanolamine 

Downstream Products

• 635752-67-9 N-benzyl-N-[1-butyl-1-(tert-butyl-dimethyl-silanyloxymethyl)-pentyl]-4-dimethylamino-2-(3-ethylamino-benzyl)-benzenesulfonamide 
• 288161-93-3 N-benzyl-N-[1-butyl-1-(tert-butyl-dimethyl-silanyloxymethyl)-pentyl]-4-dimethylamino-2-(3-nitro-benzyl)-benzenesulfonamide 
• 635752-85-1 2-(3-amino-benzyl)-N-[1-butyl-1-(tert-butyl-dimethyl-silanyloxymethyl)-pentyl]-4-dimethylamino-benzenesulfonamide 
• 288161-87-5 N-[1-butyl-1-(tert-butyl-dimethyl-silanyloxymethyl)-pentyl]-4-dimethylamino-N-methyl-2-(3-nitro-benzyl)-benzenesulfonamide 
• 288161-91-1 N-[1-butyl-1-(tert-butyl-dimethyl-silanyloxymethyl)-pentyl]-4-dimethylamino-2-(3-nitro-benzyl)-benzenesulfonamide 
• 635752-68-0 2-(3-amino-benzyl)-N-[1-butyl-1-(tert-butyl-dimethyl-silanyloxymethyl)-pentyl]-4-dimethylamino-N-methyl-benzenesulfonamide 
• 635752-98-6 N-benzyl-N-(1-butyl-1-formyl-pentyl)-4-dimethylamino-2-(3-ethylamino-benzyl)-benzenesulfonamide 
• 635752-88-4 N-[1-butyl-1-(tert-butyl-dimethyl-silanyloxymethyl)-pentyl]-4-dimethylamino-2-(4-hydroxy-benzyl)-benzenesulfonamide 
• 635752-69-1 N-[1-butyl-1-(tert-butyl-dimethyl-silanyloxymethyl)-pentyl]-4-dimethylamino-2-(3-methoxy-benzyl)-N-methyl-benzenesulfonamide 
• 635752-87-3 N-[1-butyl-1-(tert-butyl-dimethyl-silanyloxymethyl)-pentyl]-4-dimethylamino-2-(4-methoxy-benzyl)-benzenesulfonamide 
• 635752-70-4 N-[1-butyl-1-(tert-butyl-dimethyl-silanyloxymethyl)-pentyl]-4-dimethylamino-2-(4-hydroxy-benzyl)-N-methyl-benzenesulfonamide 
• 288161-90-0 N-[1-butyl-1-(tert-butyl-dimethyl-silanyloxymethyl)-pentyl]-4-dimethylamino-2-(4-methoxy-benzyl)-N-methyl-benzenesulfonamide 
• 288162-02-7 N-benzyl-N-(1-butyl-1-formyl-pentyl)-4-dimethylamino-2-(3-nitro-benzyl)-benzenesulfonamide 
• 635752-83-9 2-benzyl-N-[1-butyl-1-(tert-butyl-dimethyl-silanyloxymethyl)-pentyl]-4-dimethylamino-benzenesulfonamide 

Relevant articles and documents

A novel class of apical sodium co-dependent bile acid transporter inhibitors: The 1,2-benzothiazepines

A series of 5-aryl-3,3-dibutyl-7-(dimethylamino)-1,2-benzothiazepin-4-ol 1,1-dioxides were prepared and were found to inhibit the apical sodium co-dependent bile acid transporter (ASBT) for the potential treatment for hyperlipidemia. Several 1,2-benzothiazepines exhibited low nanomolar in vitro activity. The synthesis and initial in vitro potency data is presented for this novel class of compounds.