288260-63-9Relevant academic research and scientific papers
Synthesis of substituted cyclopropanone acetals by carbometallation and its oxidative cleavage with manganese(IV) oxide and lead(IV) oxide
Nakamura, Masaharu,Inoue, Toshihiro,Nakamura, Eiichi
, p. 300 - 306 (2007/10/03)
A variety of substituted cyclopropanone acetals were prepared by the addition of an organozinc reagent or a Grignard reagent to a substituted cyclopropenone acetal. MnO2- or PbO2-mediated oxidative ring opening reaction of the substituted cyclopropanone acetals affords β-alkoxyesters and protected β-aminoesters with high efficiency.
Asymmetric construction of quaternary carbon centers by regio- and enantiocontrolled allylzincation
Nakamura, Masaharu,Inoue, Toshihiro,Sato, Akihito,Nakamura, Eiichi
, p. 2193 - 2196 (2007/10/03)
(equation presented) An allylic zinc reagent bearing a chiral bisoxazoline ligand adds to a substituted cyclopropenone acetal to produce an optically active cyclopropanone acetal possessing a quaternary chiral center in high yield with 97.8-99.8% ee. The
