288385-37-5Relevant academic research and scientific papers
Design and synthesis of 3,5-disubstituted boron-containing 1,2,4-oxadiazoles as potential combretastatin A-4 (CA-4) analogs
Das, Bhaskar C.,Tang, Xiang-Ying,Rogler, Patrick,Evans, Todd
, p. 3947 - 3950 (2012/08/14)
We have designed and synthesized a small library of 3,5-disubstituted-1,2, 4-oxadiazole containing combretastatin A-4 (CA-4) analogs. Our objective is to increase the efficacy of the CA-4 as an anti-tubulin and antimitotic agent by substituting the cis-al
