288580-26-7Relevant academic research and scientific papers
Design, synthesis, and biological evaluation of cyclic and acyclic nitrobenzylphosphoramide mustards for E. coli nitroreductase activation
Jiang, Yongying,Han, Jiye,Yu, Chengzhi,Vass, Simon O.,Searle, Peter F.,Browne, Patrick,Knox, Richard J.,Hu, Longqin
, p. 4333 - 4343 (2007/10/03)
In efforts to obtain anticancer prodrugs for antibody-directed or gene-directed enzyme prodrug therapy using E. coli nitroreductase, a series of nitrobenzylphosphoramide mustards were designed and synthesized incorporating a strategically placed nitro gro
Nitroaryl phosphoramide compositions and methods for targeting and inhibiting undesirable cell growth or proliferation
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Page 13, (2010/02/09)
The present invention relates to nitroaryl-substituted phosphoramide prodrug compounds and methods of producing the same for use in targeting and inhibiting undesirable cell growth or proliferation.
