288588-14-7

Basic information

• Product Name: 8-Indolizinemethanamine,5,6,7,8-tetrahydro-,(8R)-(9CI)
• Synonyms: 8-Indolizinemethanamine,5,6,7,8-tetrahydro-,(8R)-(9CI)
• CAS NO: 288588-14-7
• Molecular Formula: C₉H₁₄N₂
• Molecular Weight: 0
• Product Categories: AMINETERTIARY
• Mol File: 288588-14-7.mol
• Article Data: 1

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 8-Indolizinemethanamine,5,6,7,8-tetrahydro-,(8R)-(9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: 8-Indolizinemethanamine,5,6,7,8-tetrahydro-,(8R)-(9CI)(288588-14-7)
• EPA Substance Registry System: 8-Indolizinemethanamine,5,6,7,8-tetrahydro-,(8R)-(9CI)(288588-14-7)

Safety Data

• Hazardous Substances Data: 288588-14-7(Hazardous Substances Data)

Upstream product

• 288588-11-4 (S)-2-N,N-dibenzylamino-5-N-pyrrolylpentan-1-ol 
• 288588-10-3 (S)-5-Amino-2-dibenzylamino-pentan-1-ol 
• 235425-06-6 (2S)-benzyl 4-carbamoyl-2-dibenzylaminobutyrate 
• 288588-12-5 (R)-8-N,N-dibenzylaminomethyl-5,6,7,8-tetrahydroindolizine 

Relevant articles and documents

Synthesis of enantiopure 8-aminomethylindolizines from glutamine by stereoelectronically controlled cationic cyclization

Starting from natural glutamine the synthesis of the 8- aminomethylindolizine (4b) was accomplished. The construction of the ring system was performed by employing a cationic 6-exo π-cyclization of an intermediate aziridinium salt. Transformation of the N,N-dibenzyl protected amine (4b) into the pharmacologically relevant target compound (11) is also described.