288624-89-5Relevant academic research and scientific papers
Two-fragment α-adrenolytics 2. Synthesis of alkyl(phenyl)[ω-(N-phenylpiperazino)alkyl]phosphine oxides
Reznik,Akamsin,Galyametdinova,Chernova,Shagidullin
, p. 490 - 494 (2000)
A method for the synthesis of hypotensive alkyl(phenyl)[ω-(N-phenylpiperazino)alkyl]-phosphine oxides by reacting alkyl(ω-haloalkyl)phenylphosphine oxides with N-phenylpiperazine was elaborated. Phenyl[γ-(N-phenylpiperazino)propyl]propylphosphine oxide reacts with alkyl halides to give [γ-(N-alkyl-N′-phenylpiperazinio)propyl]phenyl(propyl)oxophosphine halides.
