28863-86-7Relevant academic research and scientific papers
Umpolung Strategy with 2-Aminothiophenols: Access to 2-Arylbenzothiazine Derivatives from Alkyl Aryl Ketones
Nguyen, Thanh Binh,Retailleau, Pascal
supporting information, p. 5380 - 5384 (2020/11/02)
Strong Br?nsted acids were found to catalyze the oxidative condensation of 2-aminothiophenols with aryl alkyl ketones in DMSO to provide a wide range of complex 2-arylbenzothiazines. With acetophenones, dimeric 2-arylbenzothiazines were formed. On the other hand, the reaction with propiophenones resulted in 2:1 adducts whereas 1:1 adducts were produced with isobutyrophenones, benzoylacetonitrile and ethyl benzoylacetate. (Figure presented.).
SYNTHESIS, STRUCTURE, AND CHEMISTRY OF A 1-THIA-4-AZANAPHTHALENE
Sakoda, Vianne M.,Whittle, Robert R.,Olofson, R. A.
, p. 2635 - 2638 (2007/10/02)
From a crystal structure determination and thermal rearrangement studies, it is evident that 1-methyl-2-carbethoxy-3-phenyl-1-thia-4-azanaphthalene is an alias for a molecule more properly represented by a name emphasizing its zwitterionic character.
Reaction between 2,2'-Dithiodianiline and Activated Alkynes. Synthesis of 4H-1,4-Benzothiazines
Liso, Gaetano,Trapani, Giuseppe,Reho, Antonia,Latrofa, Andrea,Loiodice, Fulvio
, p. 567 - 572 (2007/10/02)
By the title reaction acetylenic esters (2a-c), ketones (2d-g), and the nitrile (2h) gave in all cases the corresponding 4H-1,4-benzothiazines (3) together with other products whose nature depends on the alkyne used.Thus benzothiazoline and/or benzothiazole, benzothiazepine, and vinylsulphides were obtained in the representative cases (2c, f, h) studied in detail.Some of these latter compounds have been independently synthesised by reaction of 2-aminobenzenethiol with corresponding alkyne (2).In particular conditions by the reactions between 2,2'-dithiodianiline (1) and alkynes (2f, d) we isolated bisenamine compounds (19) and (20) respectively and their intermediacy in formation of the corresponding benzothiazines (3f) and (3d) was achieved.The mechanisms of the observed reactions are also suggested.
