2887-65-2

Basic information

• Product Name: 1-(3,5-dibromo-4-hydroxy-phenyl)-propan-1-one
• CAS NO: 2887-65-2
• Molecular Weight: 307.969
• Mol File: 2887-65-2.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 1-(3,5-dibromo-4-hydroxy-phenyl)-propan-1-one(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(3,5-dibromo-4-hydroxy-phenyl)-propan-1-one(2887-65-2)
• EPA Substance Registry System: 1-(3,5-dibromo-4-hydroxy-phenyl)-propan-1-one(2887-65-2)

Safety Data

• Hazardous Substances Data: 2887-65-2(Hazardous Substances Data)

Upstream product

• 23600-76-2 2-bromophenyl propionic acid 
• 95-56-7 2-hydroxybromobenzene 
• 108-95-2 phenol 
• 70-70-2 4-hydroxypropiophenone 

Downstream Products

• 23600-57-9 2,6-Dibrom-4-<1-hydroxy-propyl>-anisol 
• 24876-03-7 1-(3,5-dibromo-4-methoxy-phenyl)-propan-1-one 

Relevant articles and documents

Synthesis, biochemical evaluation and rationalisation of a series of 3,5- dibromo derivatives of 4-hydroxyphenyl ketone-based compounds as probes of the active site of type 3 of 17β-hydroxysteroid dehydrogenase (17β-hsd3) and the role of hydrogen bonding interaction in the inhibition of 17β-HSD3

We report the synthesis, evaluation and rationalisation of the inhibitory activity of a series of 3,5-dibromo derivatives of 4-hydroxyphenyl ketone as probes of the active site of the type 3 of 17β-hydroxysteroid dehydrogenase (17β-HSD3). The results support the important role of hydrogen bonding interaction in the inhibition of 17β-HSD3.