2888-12-2Relevant academic research and scientific papers
REACTIVITY OF CARBANIONS. XVI. ALKYLATION OF ALKALI-METAL SALTS OF CH ACIDS WITH ELECTRON WITHDRAWING SUBSTITUENTS BY BUTYL BROMIDE
Solov'yanov, A. A.,Beletskaya, I. P.,Reutov, O. A.
, p. 1608 - 1611 (2007/10/02)
The rate constants for the reaction of the free carbanions and ion pairs were determined in the alkylation of lithium and cesium salts of phenylacetonitrile, ethyl diphenylacetate, ethyl phenylacetate, and bis(pentafluorophenyl)methane by butyl bromide in dimethoxyethane at 25 gradC.The reactivity of the carbanions increases with their conjugate CH acids in the following order: ethyl diphenylacetate (0.78 liter/mole.sec) bis(pentafluorophenyl)methane (2.7 liter/mole.sec) phenylacetonitrile (6.9 liter/mole.sec) ethyl phenylacetate (9.5 liter/mole.sec).
