2888-90-6

Usage

Uses

Used in Pharmaceutical and Agrochemical Industries:
Endo-Bicyclo[2.2.1]hept-5-ene-2-carbonitrile is used as a key building block in the synthesis of various pharmaceuticals and agrochemicals due to its ability to form complex organic molecules that can exhibit biological activity.
Used in Polymer and Plastics Production:
endo-Bicyclo[2.2.1]hept-5-ene-2-carbonitrile is utilized as a monomer in the production of various polymers and plastics, contributing to the development of materials with specific properties tailored for different applications.
Used in Specialty Chemicals Manufacturing:
Endo-Bicyclo[2.2.1]hept-5-ene-2-carbonitrile serves as an intermediate in the manufacturing of specialty chemicals, where its unique structure and reactivity are leveraged to create high-value products for niche applications across various industries.

InChI:InChI=1/C8H9N/c9-5-8-4-6-1-2-7(8)3-6/h1-2,6-8H,3-4H2/t6-,7+,8+/m1/s1

Upstream product

• 542-92-7 cyclopenta-1,3-diene 
• 107-13-1 acrylonitrile 
• 71338-99-3 6exo-cyano-2exo-norbornyl p-toluenesulfonate 

Downstream Products

• 2234-26-6 2-endo-norbornane carbonitrile 
• 5888-36-8 (rac)-(exo,exo)-bicyclo[2.2.1]heptane-2,5-diol 
• 95-10-3 2-aminomethylbicyclo[2.2.1]hept-5-ene 
• 5257-46-5 (bicyclo<2.2.1>heptene-5 yle-2)-1 propanone-1, endo 
• 5257-46-5 1-bicyclo(2.2.1)-hept-5-en-2-yl propanone 
• 18776-20-0 (1S,2R,4S,5S)-3-Oxa-tricyclo[3.2.1.0^2,4]octane-6-carbonitrile 
• 111099-03-7 (2R,3S)-1-Bicyclo[2.2.1]hept-5-en-2-yl-3-hydroxy-2-methyl-3-phenyl-propan-1-one 
• 111099-03-7 exo (syn 2,3 hydroxy-3 methyl-2 phenyl-3 propanone-1 yl-1)-5 bicyclo<2.2.1>heptene-2 
• 111099-03-7 endo (hydroxy-3 methyl-2 phenyl-3 propanone-1 yl-1)-5 bicyclo<2.2.1>heptene-2 
• 111099-08-2 exo (syn 2,3 methyl-2 phenyl-3 trimethylsiloxy-3 propanone-1 yl-1)-5 bicyclo<2.2.1.>heptene-2 
• 111099-08-2 endo (methyl-2 phenyl-3 trimethylsiloxy-3 propanone-1 yl)-5 bicyclo<2.2.1> heptene-2 
• 102939-69-5 (1S,2R,4S)-2-(3-Methoxy-benzyl)-bicyclo[2.2.1]hept-5-ene-2-carbaldehyde 
• 102939-75-3 (1S,4S,5R)-5-(2,2-Dibromo-vinyl)-5-(3-methoxy-benzyl)-bicyclo[2.2.1]hept-2-ene 
• 102939-73-1 [(1S,2R,4S)-2-(3-Methoxy-benzyl)-bicyclo[2.2.1]hept-5-en-2-yl]-propynoic acid methyl ester 

Relevant academic research and scientific papers

Enhanced Diels-Alder reactions: on the role of mineral catalysts and microwave irradiation in ionic liquids as recyclable media

This manuscript explores in detail the combined effect of solid supports or microwave irradiation in ionic liquids on a series of Diels-Alder reactions involving 1,3-cyclopentadiene and numerous dienophiles.

Experimental evidence to support viscosity dependence of rates of Diels-Alder reactions in solvent media

This note is aimed at ascertaining whether rates of Diels-Alder reactions depend on the viscosity of solvent media in which the reactions are performed. On the basis of the data collected from the literature and in this laboratory, it is seen in general that the rates increase in the solvents with their viscosities ranging up to ～1.2 cP. In solvents possessing viscosities above 1.2 cP, a drop in the reaction rates is observed in all cases. The effect of temperature on the above phenomena is also examined.

Rearrangements of 5- and 6-Cyano-2-norbornyl Cations

Hydroboration of the 5-norbornene-2-carbonitriles 11 afforded 5- and 6-hydroxynorbornane-2-carbonitriles (9a, 10a) along with the analogous ketones 12, 13. 5- and 6-aminonorbornane-2-carbonitriles (17a, 18a) were obtained either from the endo-brosylates 1