288863-28-5

Basic information

• Product Name: 2-hydroxy-6-phenyl-hexanenitrile
• Synonyms: 2-Hydroxy-6-phenylhexanonitril; benzenehexanenitrile, α-hydroxy-
• CAS NO: 288863-28-5
• Molecular Formula: C₁₂H₁₅NO
• Molecular Weight: 189.25
• Mol File: 288863-28-5.mol
• Article Data: 2

Chemical Properties

• Boiling Point: 355.7°C at 760 mmHg
• Flash Point: 168.9°C
• Density: 1.054g/cm³
• Vapor Pressure: 1.13E-05mmHg at 25°C
• Refractive Index: 1.533
• CAS DataBase Reference: 2-hydroxy-6-phenyl-hexanenitrile(CAS DataBase Reference)
• NIST Chemistry Reference: 2-hydroxy-6-phenyl-hexanenitrile(288863-28-5)
• EPA Substance Registry System: 2-hydroxy-6-phenyl-hexanenitrile(288863-28-5)

Safety Data

• Hazardous Substances Data: 288863-28-5(Hazardous Substances Data)

Upstream product

• 10521-91-2 5-phenylpentan-1-ol 
• 36884-28-3 5-phenyl-1-pentanal 
• 17734-38-2 ethyl 5-phenylpentanoate 
• 7677-24-9 trimethylsilyl cyanide 

Relevant articles and documents

Nickel-Catalyzed, Reductive C(sp3)?Si Cross-Coupling of α-Cyano Alkyl Electrophiles and Chlorosilanes

A nickel/zinc-catalyzed cross-electrophile coupling of alkyl electrophiles activated by an α-cyano group and chlorosilanes is reported. Elemental zinc is the stoichiometric reductant in this reductive coupling process. By this, a C(sp3)?Si bond can be formed starting from two electrophilic reactants whereas previous methods rely on the combination of carbon nucleophiles and silicon electrophiles or vice versa.