28892-73-1 Usage
Description
3-Hydroxy-2-methylvaleric acid is a hydroxy fatty acid, an organic compound that serves as an intermediate in the biosynthesis of the branched-chain fatty acid 3-hydroxy-2-methylbutyric acid. It is involved in the metabolism of the amino acid leucine and is a metabolite of isobutyric acid, with potential roles as a signaling molecule or a bioactive compound. 3-Hydroxy-2-methylvaleric acid has been studied for its therapeutic applications, particularly in metabolic disorders, lipid metabolism, and insulin sensitivity.
Uses
Used in Pharmaceutical Industry:
3-Hydroxy-2-methylvaleric acid is used as a therapeutic agent for its potential role in treating various metabolic disorders. Its involvement in the metabolism of leucine and its status as a metabolite of isobutyric acid suggest that it could have beneficial effects on lipid metabolism and insulin sensitivity, making it a promising candidate for the development of treatments for conditions related to these metabolic pathways.
Used in Research Applications:
In the field of scientific research, 3-Hydroxy-2-methylvaleric acid is used as a subject of study to explore its potential as a signaling molecule or a bioactive compound. Understanding its role in cellular processes and its interactions with other biochemical pathways can provide insights into the development of new therapeutic strategies and interventions for metabolic-related diseases.
Used in Nutritional Supplements:
3-Hydroxy-2-methylvaleric acid may also be used in the development of nutritional supplements aimed at supporting healthy lipid metabolism and improving insulin sensitivity. Its presence in supplements could potentially offer benefits to individuals looking to manage their metabolic health through dietary means.
Check Digit Verification of cas no
The CAS Registry Mumber 28892-73-1 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 2,8,8,9 and 2 respectively; the second part has 2 digits, 7 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 28892-73:
(7*2)+(6*8)+(5*8)+(4*9)+(3*2)+(2*7)+(1*3)=161
161 % 10 = 1
So 28892-73-1 is a valid CAS Registry Number.
InChI:InChI=1/C6H12O3/c1-3-5(7)4(2)6(8)9/h4-5,7H,3H2,1-2H3,(H,8,9)
28892-73-1Relevant articles and documents
Process development of halaven: Synthesis of the C14-C35 fragment via iterative nozaki-hiyama-kishi reaction-williamson ether cyclization
Austad, Brian C.,Benayoud, Farid,Calkins, Trevor L.,Campagna, Silvio,Chase, Charles E.,Choi, Hyeong-Wook,Christ, William,Costanzo, Robert,Cutter, James,Endo, Atsushi,Fang, Francis G.,Hu, Yongbo,Lewis, Bryan M.,Lewis, Michael D.,McKenna, Shawn,Noland, Thomas A.,Orr, John D.,Pesant, Marc,Schnaderbeck, Matthew J.,Wilkie, Gordon D.,Abe, Taichi,Asai, Naoki,Asai, Yumi,Kayano, Akio,Kimoto, Yuichi,Komatsu, Yuki,Kubota, Manabu,Kuroda, Hirofumi,Mizuno, Masanori,Nakamura, Taiju,Omae, Takao,Ozeki, Naoki,Suzuki, Taeko,Takigawa, Teiji,Watanabe, Tomohiro,Yoshizawa, Kazuhiro
, p. 327 - 332 (2013/04/10)
Multikilogram manufacturing process of the Halaven C14-C35 fragment is described. The synthesis features convergent assembly of subunits by iterative asymmetric Ni/Cr-mediated coupling executed in fixed equipment. Georg Thieme Verlag Stuttgart - New York.
Diastereoselectivity in heterogeneous catalytic hydrogenation of Baylis-Hillman adducts. Total synthesis of (±)-sitophilate
Mateus, Cristiano R,Feltrin, Melissa P,Costa, Ana M,Coelho, Fernando,Almeida, Wanda P
, p. 6901 - 6908 (2007/10/03)
We describe herein a highly diastereoselective total synthesis of racemic sitophilate, based on the results obtained in a diastereoselective heterogeneous catalytic hydrogenation reaction of a set of Baylis-Hillman adducts originating from aliphatic aldehydes.
SHORT SYNTHESIS OF RACEMIC SITOPHYLATE, THE AGGREGATION PHEROMONE OF A GRANARY WEEVIL
Moiseenkov, A. M.,Cheskis, B. A.,Shpiro, N. A.
, p. 121 - 122 (2007/10/02)
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