28917-26-2

Usage

Uses

Used in Medicinal Chemistry:
(3Z)-3-1-[(2-phenylethyl)amino]ethylidenedihydrofuran-2(3H)-one is used as a potential drug candidate for the development of new pharmaceuticals. Its unique structure and functional groups make it a promising candidate for the treatment of various diseases and conditions.
Used in Organic Synthesis:
(3Z)-3-1-[(2-phenylethyl)amino]ethylidenedihydrofuran-2(3H)-one is used as a building block for the synthesis of other complex organic compounds. Its versatile structure and functional groups allow for further modification and incorporation into a wide range of chemical reactions, making it a valuable component in the development of new materials and compounds.
Used in Scientific Research:
(3Z)-3-1-[(2-phenylethyl)amino]ethylidenedihydrofuran-2(3H)-one is used as a target for further research and development in various scientific fields. Its unique structure and functional groups make it an interesting subject for study, with potential applications in areas such as drug discovery, materials science, and chemical biology.

Upstream product

• 517-23-7 3-acetyl-2-oxo-4,5-dihydrofuran 
• 6926-44-9 phenethyl azide 
• 64-04-0 phenethylamine 

Relevant academic research and scientific papers

A mild and efficient method for the synthesis of vinylogous carbamates from alkyl azides

A mild and efficient one-pot method for the synthesis of vinylogous carbamates is reported starting from alkyl azides under a hydrogen atmosphere using 10% Pd/C. The resulting products are useful intermediates for the synthesis of heterocyclic compounds, natural products, and in peptidomimetics.

A new synthesis of alkyl-1-alkyl-2-methylpyrrole-3-carboxylates by ring transformation of 2-chloro-2-acetimidoylbutyrolactones

Reaction of 2-chloro-2-acetimidoylbutyrolactones with sodium methoxide or sodium ethoxide in the corresponding alcohol provides a facile one-step synthesis of methyl or ethyl 1-alkyl-2-methylpyrrole-3-carboxylates from readily available starting materials.

REACTION OF α-ACETYLBUTYROLACTONE WITH AMINES

The reaction of α-acetylbutyrolactone and its ethylene ketal derivative with primary amines were investigated.Depending on the reaction conditions derivatives of butyrolactone (-) or urea (, ) or γ-hydroxybutyric acid (-) were obtained.The cyclisation reaction of γ-hydroxybutyric acid derivatives (-) to the corresponding 1,3-disubstituted pyrrolidinone-2 were also examined.Keywords: α-acetylbutyrolactone, γ-hydroxybutyric acid, elemental and spectral analysis, cyclization reaction